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Discovery of tropinone-thiazole derivatives as potent caspase 3/7 activators, and noncompetitive tyrosinase inhibitors with high antiproliferative activity: Rational design, one-pot tricomponent synthesis, and lipophilicity determination.
Piechowska K, Świtalska M, Cytarska J, Jaroch K, Łuczykowski K, Chałupka J, Wietrzyk J, Misiura K, Bojko B, Kruszewski S, Łączkowski KZ. Piechowska K, et al. Among authors: cytarska j. Eur J Med Chem. 2019 Aug 1;175:162-171. doi: 10.1016/j.ejmech.2019.05.006. Epub 2019 May 4. Eur J Med Chem. 2019. PMID: 31082763 Free article.
Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives.
Łączkowski KZ, Anusiak J, Świtalska M, Dzitko K, Cytarska J, Baranowska-Łączkowska A, Plech T, Paneth A, Wietrzyk J, Białczyk J. Łączkowski KZ, et al. Among authors: cytarska j. Med Chem Res. 2018;27(4):1131-1148. doi: 10.1007/s00044-018-2136-6. Epub 2018 Feb 6. Med Chem Res. 2018. PMID: 29576720 Free PMC article.
Benzo[b]thiophene-thiazoles as potent anti-Toxoplasma gondii agents: Design, synthesis, tyrosinase/tyrosine hydroxylase inhibitors, molecular docking study, and antioxidant activity.
Rosada B, Bekier A, Cytarska J, Płaziński W, Zavyalova O, Sikora A, Dzitko K, Łączkowski KZ. Rosada B, et al. Among authors: cytarska j. Eur J Med Chem. 2019 Dec 15;184:111765. doi: 10.1016/j.ejmech.2019.111765. Epub 2019 Oct 10. Eur J Med Chem. 2019. PMID: 31629163 Free article.
Tropinone-Derived Alkaloids as Potent Anticancer Agents: Synthesis, Tyrosinase Inhibition, Mechanism of Action, DFT Calculation, and Molecular Docking Studies.
Piechowska K, Mizerska-Kowalska M, Zdzisińska B, Cytarska J, Baranowska-Łączkowska A, Jaroch K, Łuczykowski K, Płaziński W, Bojko B, Kruszewski S, Misiura K, Łączkowski KZ. Piechowska K, et al. Among authors: cytarska j. Int J Mol Sci. 2020 Nov 28;21(23):9050. doi: 10.3390/ijms21239050. Int J Mol Sci. 2020. PMID: 33260768 Free PMC article.
12 results