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Page 1
Structure-Guided Identification of Resistance Breaking Antimalarial N‑Myristoyltransferase Inhibitors.
Schlott AC, Mayclin S, Reers AR, Coburn-Flynn O, Bell AS, Green J, Knuepfer E, Charter D, Bonnert R, Campo B, Burrows J, Lyons-Abbott S, Staker BL, Chung CW, Myler PJ, Fidock DA, Tate EW, Holder AA. Schlott AC, et al. Among authors: mayclin s. Cell Chem Biol. 2019 Jul 18;26(7):991-1000.e7. doi: 10.1016/j.chembiol.2019.03.015. Epub 2019 May 9. Cell Chem Biol. 2019. PMID: 31080074 Free PMC article.
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba.
Tillery L, Barrett K, Goldstein J, Lassner JW, Osterhout B, Tran NL, Xu L, Young RM, Craig J, Chun I, Dranow DM, Abendroth J, Delker SL, Davies DR, Mayclin SJ, Calhoun B, Bolejack MJ, Staker B, Subramanian S, Phan I, Lorimer DD, Myler PJ, Edwards TE, Kyle DE, Rice CA, Morris JC, Leahy JW, Manetsch R, Barrett LK, Smith CL, Van Voorhis WC. Tillery L, et al. Among authors: mayclin sj. PLoS One. 2021 Mar 24;16(3):e0241738. doi: 10.1371/journal.pone.0241738. eCollection 2021. PLoS One. 2021. PMID: 33760815 Free PMC article.
Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis.
Porter I, Neal T, Walker Z, Hayes D, Fowler K, Billups N, Rhoades A, Smith C, Smith K, Staker BL, Dranow DM, Mayclin SJ, Subramanian S, Edwards TE, Myler PJ, Asojo OA. Porter I, et al. Among authors: mayclin sj. Acta Crystallogr F Struct Biol Commun. 2022 Jan 1;78(Pt 1):31-38. doi: 10.1107/S2053230X21013078. Epub 2022 Jan 1. Acta Crystallogr F Struct Biol Commun. 2022. PMID: 34981773 Free PMC article.
Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major.
Iwasaki J, Lorimer DD, Vivoli-Vega M, Kibble EA, Peacock CS, Abendroth J, Mayclin SJ, Dranow DM, Pierce PG, Fox D, Lewis M, Bzdyl NM, Kristensen SS, Inglis TJJ, Kahler CM, Bond CS, Hasenkopf A, Seufert F, Schmitz J, Marshall LE, Scott AE, Norville IH, Myler PJ, Holzgrabe U, Harmer NJ, Sarkar-Tyson M. Iwasaki J, et al. Among authors: mayclin sj. J Antimicrob Chemother. 2022 May 29;77(6):1625-1634. doi: 10.1093/jac/dkac065. J Antimicrob Chemother. 2022. PMID: 35245364 Free PMC article.
23 results