Østergaard S - Search Results

1

Modified Peptide YY Molecule Attenuates the Activity of NPY/AgRP Neurons and Reduces Food Intake in Male Mice.

Jones ES, Nunn N, Chambers AP, Østergaard S, Wulff BS, Luckman SM. Jones ES, et al. Among authors: ostergaard s. Endocrinology. 2019 Nov 1;160(11):2737-2747. doi: 10.1210/en.2019-00100. Endocrinology. 2019. PMID: 31074796 Free PMC article.

2

Metabolism of peptide YY 3-36 in Göttingen mini-pig and rhesus monkey.

Olsen J, Kofoed J, Østergaard S, Wulff BS, Nielsen FS, Jorgensen R. Olsen J, et al. Among authors: ostergaard s. Peptides. 2016 Apr;78:59-67. doi: 10.1016/j.peptides.2016.01.010. Epub 2016 Jan 14. Peptides. 2016. PMID: 26774588

3

Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y₂ Receptor.

Xu B, Vasile S, Østergaard S, Paulsson JF, Pruner J, Åqvist J, Wulff BS, Gutiérrez-de-Terán H, Larhammar D. Xu B, et al. Among authors: ostergaard s. Mol Pharmacol. 2018 Apr;93(4):323-334. doi: 10.1124/mol.117.110627. Epub 2018 Jan 24. Mol Pharmacol. 2018. PMID: 29367257

4

Design of Y₂ Receptor Selective and Proteolytically Stable PYY_3-36 Analogues.

Østergaard S, Kofoed J, Paulsson JF, Madsen KG, Jorgensen R, Wulff BS. Østergaard S, et al. J Med Chem. 2018 Dec 13;61(23):10519-10530. doi: 10.1021/acs.jmedchem.8b01046. Epub 2018 Nov 20. J Med Chem. 2018. PMID: 30399314

5

The Design of a GLP-1/PYY Dual Acting Agonist.

Østergaard S, Paulsson JF, Kjaergaard Gerstenberg M, Wulff BS. Østergaard S, et al. Angew Chem Int Ed Engl. 2021 Apr 6;60(15):8268-8275. doi: 10.1002/anie.202016464. Epub 2021 Mar 1. Angew Chem Int Ed Engl. 2021. PMID: 33448563

6

Rational Development of Stable PYY_3-36 Peptide Y₂ Receptor Agonists.

Poulsen C, Pedersen MØ, Wahlund PO, Sjölander A, Thomsen JK, Conde-Frieboes KW, Paulsson JF, Wulff BS, Østergaard S. Poulsen C, et al. Among authors: ostergaard s. Pharm Res. 2021 Aug;38(8):1369-1385. doi: 10.1007/s11095-021-03077-x. Epub 2021 Jul 16. Pharm Res. 2021. PMID: 34272643

7

The effect of fatty diacid acylation of human PYY_3-36 on Y₂ receptor potency and half-life in minipigs.

Østergaard S, Paulsson JF, Kofoed J, Zosel F, Olsen J, Jeppesen CB, Spetzler J, Ynddal L, Schleiss LG, Christoffersen BØ, Raun K, Sensfuss U, Nielsen FS, Jørgensen R, Wulff BS. Østergaard S, et al. Sci Rep. 2021 Oct 27;11(1):21179. doi: 10.1038/s41598-021-00654-3. Sci Rep. 2021. PMID: 34707178 Free PMC article.

8

A parallel semisynthetic approach for structure-activity relationship studies of peptide YY.

Albertsen L, Østergaard S, Paulsson JF, Norrild JC, Strømgaard K. Albertsen L, et al. Among authors: ostergaard s. ChemMedChem. 2013 Sep;8(9):1505-13, 1422. doi: 10.1002/cmdc.201300290. Epub 2013 Jul 31. ChemMedChem. 2013. PMID: 23907926

9

The effect of acylation with fatty acids and other modifications on HLA class II:peptide binding and T cell stimulation for three model peptides.

Schultz HS, Østergaard S, Sidney J, Lamberth K, Sette A. Schultz HS, et al. Among authors: ostergaard s. PLoS One. 2018 May 14;13(5):e0197407. doi: 10.1371/journal.pone.0197407. eCollection 2018. PLoS One. 2018. PMID: 29758051 Free PMC article.

10

Redefining peptide therapeutics with semaglutide.

Kruse T, Østergaard S. Kruse T, et al. Among authors: ostergaard s. Nat Chem. 2024 Feb;16(2):296. doi: 10.1038/s41557-023-01434-4. Nat Chem. 2024. PMID: 38321235 No abstract available.

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