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Synthetic TRuC receptors engaging the complete T cell receptor for potent anti-tumor response.
Baeuerle PA, Ding J, Patel E, Thorausch N, Horton H, Gierut J, Scarfo I, Choudhary R, Kiner O, Krishnamurthy J, Le B, Morath A, Baldeviano GC, Quinn J, Tavares P, Wei Q, Weiler S, Maus MV, Getts D, Schamel WW, Hofmeister R. Baeuerle PA, et al. Among authors: schamel ww. Nat Commun. 2019 May 7;10(1):2087. doi: 10.1038/s41467-019-10097-0. Nat Commun. 2019. PMID: 31064990 Free PMC article.
A Cholesterol-Based Allostery Model of T Cell Receptor Phosphorylation.
Swamy M, Beck-Garcia K, Beck-Garcia E, Hartl FA, Morath A, Yousefi OS, Dopfer EP, Molnár E, Schulze AK, Blanco R, Borroto A, Martín-Blanco N, Alarcon B, Höfer T, Minguet S, Schamel WW. Swamy M, et al. Among authors: schamel ww. Immunity. 2016 May 17;44(5):1091-101. doi: 10.1016/j.immuni.2016.04.011. Immunity. 2016. PMID: 27192576 Free article.
A window of opportunity for cooperativity in the T Cell Receptor.
Martin-Blanco N, Blanco R, Alda-Catalinas C, Bovolenta ER, Oeste CL, Palmer E, Schamel WW, Lythe G, Molina-París C, Castro M, Alarcon B. Martin-Blanco N, et al. Among authors: schamel ww. Nat Commun. 2018 Jul 5;9(1):2618. doi: 10.1038/s41467-018-05050-6. Nat Commun. 2018. PMID: 29976994 Free PMC article.
αβ and γδ T cell receptors: Similar but different.
Morath A, Schamel WW. Morath A, et al. Among authors: schamel ww. J Leukoc Biol. 2020 Jun;107(6):1045-1055. doi: 10.1002/JLB.2MR1219-233R. Epub 2020 Jan 29. J Leukoc Biol. 2020. PMID: 31994778 Review.
154 results