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Mapping Interindividual Variability of Toxicodynamics Using High-Throughput Transcriptomics and Primary Human Hepatocytes from Fifty Donors.
Niemeijer M, Więcek W, Fu S, Huppelschoten S, Bouwman P, Baze A, Parmentier C, Richert L, Paules RS, Bois FY, van de Water B. Niemeijer M, et al. Among authors: bois fy. Environ Health Perspect. 2024 Mar;132(3):37005. doi: 10.1289/EHP11891. Epub 2024 Mar 18. Environ Health Perspect. 2024. PMID: 38498338 Free PMC article.
Understanding Interindividual Variability in the Drug Interaction of a Highly Extracted CYP1A2 Substrate Tizanidine: Application of a Permeability-Limited Multicompartment Liver Model in a Population Based Physiologically Based Pharmacokinetic Framework.
Zhang M, Fisher C, Gardner I, Pan X, Kilford P, Bois FY, Jamei M. Zhang M, et al. Among authors: bois fy. Drug Metab Dispos. 2022 Jul;50(7):957-967. doi: 10.1124/dmd.121.000818. Epub 2022 May 3. Drug Metab Dispos. 2022. PMID: 35504655
207 results