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DNA methylation at an enhancer of the three prime repair exonuclease 2 gene (TREX2) is linked to gene expression and survival in laryngeal cancer.
Weigel C, Chaisaingmongkol J, Assenov Y, Kuhmann C, Winkler V, Santi I, Bogatyrova O, Kaucher S, Bermejo JL, Leung SY, Chan TL, Lasitschka F, Bohrer MH, Marx A, Haußen RH, Herold-Mende C, Dyckhoff G, Boukamp P, Delank KW, Hörmann K, Lippert BM, Baier G, Dietz A, Oakes CC, Plass C, Becher H, Schmezer P, Ramroth H, Popanda O. Weigel C, et al. Among authors: becher h. Clin Epigenetics. 2019 May 3;11(1):67. doi: 10.1186/s13148-019-0666-5. Clin Epigenetics. 2019. PMID: 31053176 Free PMC article.
Laryngeal cancer risk in Caucasians is associated with alcohol and tobacco consumption but not modified by genetic polymorphisms in class I alcohol dehydrogenases ADH1B and ADH1C, and glutathione-S-transferases GSTM1 and GSTT1.
Risch A, Ramroth H, Raedts V, Rajaee-Behbahani N, Schmezer P, Bartsch H, Becher H, Dietz A. Risch A, et al. Among authors: becher h. Pharmacogenetics. 2003 Apr;13(4):225-30. doi: 10.1097/00008571-200304000-00007. Pharmacogenetics. 2003. PMID: 12668919
636 results