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Site-specific replacement of phosphorothioate with alkyl phosphonate linkages enhances the therapeutic profile of gapmer ASOs by modulating interactions with cellular proteins.
Migawa MT, Shen W, Wan WB, Vasquez G, Oestergaard ME, Low A, De Hoyos CL, Gupta R, Murray S, Tanowitz M, Bell M, Nichols JG, Gaus H, Liang XH, Swayze EE, Crooke ST, Seth PP. Migawa MT, et al. Among authors: bell m. Nucleic Acids Res. 2019 Jun 20;47(11):5465-5479. doi: 10.1093/nar/gkz247. Nucleic Acids Res. 2019. PMID: 31034558 Free PMC article.
Chemical modification of PS-ASO therapeutics reduces cellular protein-binding and improves the therapeutic index.
Shen W, De Hoyos CL, Migawa MT, Vickers TA, Sun H, Low A, Bell TA 3rd, Rahdar M, Mukhopadhyay S, Hart CE, Bell M, Riney S, Murray SF, Greenlee S, Crooke RM, Liang XH, Seth PP, Crooke ST. Shen W, et al. Among authors: bell ta 3rd, bell m. Nat Biotechnol. 2019 Jun;37(6):640-650. doi: 10.1038/s41587-019-0106-2. Epub 2019 Apr 29. Nat Biotechnol. 2019. PMID: 31036929
International Perspective on Social Cognition in Schizophrenia: Current Stage and the Next Steps.
Corbera S, Kurtz MM, Achim AM, Agostoni G, Amado I, Assaf M, Barlati S, Bechi M, Cavallaro R, Ikezawa S, Okano H, Okubo R, Penadés R, Uchino T, Vita A, Yamada Y, Bell MD. Corbera S, et al. Among authors: bell md. Eur Psychiatry. 2025 Jan 15:1-72. doi: 10.1192/j.eurpsy.2024.1776. Online ahead of print. Eur Psychiatry. 2025. PMID: 39812093 Review. No abstract available.
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
Pickering H, Schaenman J, Phan HV, Maguire C, Tsitsiklis A, Rouphael N, Higuita NIA, Atkinson MA, Brakenridge S, Fung M, Messer W; IMPACC Network; Salehi-Rad R, Altman MC, Becker PM, Bosinger SE, Eckalbar W, Hoch A, Doni Jayavelu N, Kim-Schulze S, Jenkins M, Kleinstein SH, Krammer F, Maecker HT, Ozonoff A, Diray-Arce J, Shaw A, Baden L, Levy O, Reed EF, Langelier CR. Pickering H, et al. Nat Commun. 2025 Jan 10;16(1):586. doi: 10.1038/s41467-025-55823-z. Nat Commun. 2025. PMID: 39794319 Free PMC article.
Rapid climate action is needed: comparing heat vs. COVID-19-related mortality.
Batibeniz F, Seneviratne SI, Jha S, Ribeiro A, Suarez Gutierrez L, Raible CC, Malhotra A, Armstrong B, Bell ML, Lavigne E, Gasparrini A, Guo Y, Hashizume M, Masselot P, da Silva SP, Royé D, Sera F, Tong S, Urban A, Vicedo-Cabrera AM. Batibeniz F, et al. Among authors: bell ml. Sci Rep. 2025 Jan 6;15(1):1002. doi: 10.1038/s41598-024-82788-8. Sci Rep. 2025. PMID: 39762298 Free PMC article.
Education Research: Utilization of Simulation in Residency Programs: A Survey of Adult Neurology Residency Program Directors.
Ghoshal S, Albin CSW, Malhotra NA, Asonye I, Budrow J, Stainman R, Kurzweil A, Bell M, Ford J, Kleyman I, Massad N, Mikhaeil-Demo Y, Wasserstrom B, Tchopev Z, Morris NA. Ghoshal S, et al. Among authors: bell m. Neurol Educ. 2024 Nov 14;3(4):e200156. doi: 10.1212/NE9.0000000000200156. eCollection 2024 Dec. Neurol Educ. 2024. PMID: 39748891 Free PMC article.
3,835 results