Liguori MJ - Search Results

1

Potential mechanisms of target-independent uptake and toxicity of antibody-drug conjugates.

Mahalingaiah PK, Ciurlionis R, Durbin KR, Yeager RL, Philip BK, Bawa B, Mantena SR, Enright BP, Liguori MJ, Van Vleet TR. Mahalingaiah PK, et al. Among authors: liguori mj. Pharmacol Ther. 2019 Aug;200:110-125. doi: 10.1016/j.pharmthera.2019.04.008. Epub 2019 Apr 24. Pharmacol Ther. 2019. PMID: 31028836 Review.

2

Role of cytochrome P450c17α in dibromoacetic acid-induced testicular toxicity in rats.

Carr TL, Ciurlionis R, Milicic I, Whitney K, Liguori MJ, Warder SE, Strakhova MI, Blomme EA. Carr TL, et al. Among authors: liguori mj. Arch Toxicol. 2011 May;85(5):513-23. doi: 10.1007/s00204-010-0600-2. Epub 2010 Nov 3. Arch Toxicol. 2011. PMID: 21046364

3

Screening Strategies and Methods for Better Off-Target Liability Prediction and Identification of Small-Molecule Pharmaceuticals.

Van Vleet TR, Liguori MJ, Lynch JJ 3rd, Rao M, Warder S. Van Vleet TR, et al. Among authors: liguori mj. SLAS Discov. 2019 Jan;24(1):1-24. doi: 10.1177/2472555218799713. Epub 2018 Sep 10. SLAS Discov. 2019. PMID: 30196745 Free article. Review.

4

Comparison of RNA-Seq and Microarray Gene Expression Platforms for the Toxicogenomic Evaluation of Liver From Short-Term Rat Toxicity Studies.

Rao MS, Van Vleet TR, Ciurlionis R, Buck WR, Mittelstadt SW, Blomme EAG, Liguori MJ. Rao MS, et al. Among authors: liguori mj. Front Genet. 2019 Jan 22;9:636. doi: 10.3389/fgene.2018.00636. eCollection 2018. Front Genet. 2019. PMID: 30723492 Free PMC article.

5

An Overview of Machine Learning and Big Data for Drug Toxicity Evaluation.

Vo AH, Van Vleet TR, Gupta RR, Liguori MJ, Rao MS. Vo AH, et al. Among authors: liguori mj. Chem Res Toxicol. 2020 Jan 21;33(1):20-37. doi: 10.1021/acs.chemrestox.9b00227. Epub 2019 Nov 22. Chem Res Toxicol. 2020. PMID: 31625725 Review.

6

Reduced hepatic global hydroxymethylation in mice treated with non-genotoxic carcinogens is transiently reversible with a methyl supplemented diet.

Sharapova T, Talaty N, Buck WR, Fossey S, Liguori MJ, Van Vleet TR. Sharapova T, et al. Among authors: liguori mj. Toxicol Appl Pharmacol. 2021 Mar 15;415:115439. doi: 10.1016/j.taap.2021.115439. Epub 2021 Feb 5. Toxicol Appl Pharmacol. 2021. PMID: 33549593 Free article.

7

Novel Computational Approach to Predict Off-Target Interactions for Small Molecules.

Rao MS, Gupta R, Liguori MJ, Hu M, Huang X, Mantena SR, Mittelstadt SW, Blomme EAG, Van Vleet TR. Rao MS, et al. Among authors: liguori mj. Front Big Data. 2019 Jul 17;2:25. doi: 10.3389/fdata.2019.00025. eCollection 2019. Front Big Data. 2019. PMID: 33693348 Free PMC article.

8

Preclinical species gene expression database: Development and meta-analysis.

Krause C, Suwada K, Blomme EAG, Kowalkowski K, Liguori MJ, Mahalingaiah PK, Mittelstadt S, Peterson R, Rendino L, Vo A, Van Vleet TR. Krause C, et al. Among authors: liguori mj. Front Genet. 2023 Jan 17;13:1078050. doi: 10.3389/fgene.2022.1078050. eCollection 2022. Front Genet. 2023. PMID: 36733943 Free PMC article.

9

Off-target pharmacological activity at various kinases: Potential functional and pathological side effects.

Green JR, Mahalingaiah PKS, Gopalakrishnan SM, Liguori MJ, Mittelstadt SW, Blomme EAG, Van Vleet TR. Green JR, et al. Among authors: liguori mj. J Pharmacol Toxicol Methods. 2023 Sep-Oct;123:107468. doi: 10.1016/j.vascn.2023.107468. Epub 2023 Aug 6. J Pharmacol Toxicol Methods. 2023. PMID: 37553032

10

AhR activation underlies the CYP1A autoinduction by A-998679 in rats.

Liguori MJ, Lee CH, Liu H, Ciurlionis R, Ditewig AC, Doktor S, Andracki ME, Gagne GD, Waring JF, Marsh KC, Gopalakrishnan M, Blomme EA, Yang Y. Liguori MJ, et al. Front Genet. 2012 Oct 26;3:213. doi: 10.3389/fgene.2012.00213. eCollection 2012. Front Genet. 2012. PMID: 23112805 Free PMC article.

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