Engler F - Search Results

1

A Proliferation Inducing Ligand (APRIL) targeted antibody is a safe and effective treatment of murine IgA nephropathy.

Myette JR, Kano T, Suzuki H, Sloan SE, Szretter KJ, Ramakrishnan B, Adari H, Deotale KD, Engler F, Shriver Z, Wollacott AM, Suzuki Y, Pereira BJG. Myette JR, et al. Among authors: engler f. Kidney Int. 2019 Jul;96(1):104-116. doi: 10.1016/j.kint.2019.01.031. Epub 2019 Mar 16. Kidney Int. 2019. PMID: 31027890 Free article.

2

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG₂ Monoclonal Antibody, in Healthy Volunteers.

Mathur M, Barratt J, Suzuki Y, Engler F, Pasetti MF, Yarbrough J, Sloan S, Oldach D. Mathur M, et al. Among authors: engler f. Kidney Int Rep. 2022 Feb 8;7(5):993-1003. doi: 10.1016/j.ekir.2022.01.1073. eCollection 2022 May. Kidney Int Rep. 2022. PMID: 35570983 Free PMC article.

3

Safety and efficacy of monoclonal antibody VIS410 in adults with uncomplicated influenza A infection: Results from a randomized, double-blind, phase-2, placebo-controlled study.

Hershberger E, Sloan S, Narayan K, Hay CA, Smith P, Engler F, Jeeninga R, Smits S, Trevejo J, Shriver Z, Oldach D. Hershberger E, et al. Among authors: engler f. EBioMedicine. 2019 Feb;40:574-582. doi: 10.1016/j.ebiom.2018.12.051. Epub 2019 Jan 9. EBioMedicine. 2019. PMID: 30638863 Free PMC article. Clinical Trial.

4

Physiologically Based Modeling of the Pharmacokinetics of "Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibodies in Colorectal Cancer Xenograft Mouse Models.

Polli JR, Engler FA, Balthasar JP. Polli JR, et al. J Pharm Sci. 2019 Jan;108(1):674-691. doi: 10.1016/j.xphs.2018.09.037. Epub 2018 Oct 12. J Pharm Sci. 2019. PMID: 30321546 Free PMC article.

5

Investigation of the influence of nephropathy on monoclonal antibody disposition: a pharmacokinetic study in a mouse model of diabetic nephropathy.

Engler FA, Zheng B, Balthasar JP. Engler FA, et al. Pharm Res. 2014 May;31(5):1185-93. doi: 10.1007/s11095-013-1241-y. Epub 2013 Nov 8. Pharm Res. 2014. PMID: 24203494

6

"Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibody Leads to Greater Plasma and Tumor Exposure in a Mouse Model of Colorectal Cancer.

Engler FA, Polli JR, Li T, An B, Otteneder M, Qu J, Balthasar JP. Engler FA, et al. J Pharmacol Exp Ther. 2018 Jul;366(1):205-219. doi: 10.1124/jpet.117.246900. Epub 2018 May 7. J Pharmacol Exp Ther. 2018. PMID: 29735609 Free PMC article.

7

Development and validation of an enzyme-linked immunosorbent assay for the quantification of gelonin in mouse plasma.

Engler FA, Balthasar JP. Engler FA, et al. J Immunoassay Immunochem. 2016;37(6):611-22. doi: 10.1080/15321819.2016.1182551. J Immunoassay Immunochem. 2016. PMID: 27135787

8

Electron transfer dissociation coupled to an Orbitrap analyzer may promise a straightforward and accurate sequencing of disulfide-bridged cyclic peptides: a case study.

Duan X, Engler FA, Qu J. Duan X, et al. J Mass Spectrom. 2010 Dec;45(12):1477-82. doi: 10.1002/jms.1857. J Mass Spectrom. 2010. PMID: 21031361 Free PMC article. No abstract available.

9

Determination of the Proteomic Response to Lapatinib Treatment using a comprehensive and reproducible ion-current-based proteomics strategy.

O'Connell K, Li J, Engler F, Hennessy K, O'Neill F, Straubinger RM, Qu J, O'Connor R. O'Connell K, et al. Among authors: engler f. J Proteom Genom Res. 2013;1(3):27-42. doi: 10.14302/issn.2326-0793.jpgr-13-257. Epub 2013 Sep 8. J Proteom Genom Res. 2013. PMID: 29046878 Free PMC article.

10

Combinatorial peptide ligand library treatment followed by a dual-enzyme, dual-activation approach on a nanoflow liquid chromatography/orbitrap/electron transfer dissociation system for comprehensive analysis of swine plasma proteome.

Tu C, Li J, Young R, Page BJ, Engler F, Halfon MS, Canty JM Jr, Qu J. Tu C, et al. Among authors: engler f. Anal Chem. 2011 Jun 15;83(12):4802-13. doi: 10.1021/ac200376m. Epub 2011 May 26. Anal Chem. 2011. PMID: 21491903 Free PMC article.

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