Huang M - Search Results

1

Stereodivergent Protein Engineering of a Lipase To Access All Possible Stereoisomers of Chiral Esters with Two Stereocenters.

Xu J, Cen Y, Singh W, Fan J, Wu L, Lin X, Zhou J, Huang M, Reetz MT, Wu Q. Xu J, et al. Among authors: huang m. J Am Chem Soc. 2019 May 15;141(19):7934-7945. doi: 10.1021/jacs.9b02709. Epub 2019 May 2. J Am Chem Soc. 2019. PMID: 31023008

2

Reaction Mechanism of Isopentenyl Phosphate Kinase: A QM/MM Study.

McClory J, Timson DJ, Singh W, Zhang J, Huang M. McClory J, et al. Among authors: huang m. J Phys Chem B. 2017 Dec 14;121(49):11062-11071. doi: 10.1021/acs.jpcb.7b08770. Epub 2017 Nov 30. J Phys Chem B. 2017. PMID: 29155589

3

Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications.

McAuley M, Mesa-Torres N, McFall A, Morris S, Huang M, Pey AL, Timson DJ. McAuley M, et al. Among authors: huang m. Chembiochem. 2018 May 18;19(10):1088-1095. doi: 10.1002/cbic.201800025. Epub 2018 Apr 26. Chembiochem. 2018. PMID: 29505688

4

Are the Apo Proteins Suitable for the Rational Discovery of Allosteric Drugs?

An X, Lu S, Song K, Shen Q, Huang M, Yao X, Liu H, Zhang J. An X, et al. Among authors: huang m. J Chem Inf Model. 2019 Jan 28;59(1):597-604. doi: 10.1021/acs.jcim.8b00735. Epub 2018 Dec 20. J Chem Inf Model. 2019. PMID: 30525607

5

"Top" or "bottom" switches of a cyclohexanone monooxygenase controlling the enantioselectivity of the sandwiched substrate.

Hu Y , Wang J , Cen Y , Zheng H , Huang M , Lin X , Wu Q . Hu Y , et al. Among authors: huang m. Chem Commun (Camb). 2019 Feb 14;55(15):2198-2201. doi: 10.1039/c8cc09951k. Chem Commun (Camb). 2019. PMID: 30702095

6

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution.

Cen Y, Singh W, Arkin M, Moody TS, Huang M, Zhou J, Wu Q, Reetz MT. Cen Y, et al. Among authors: huang m. Nat Commun. 2019 Jul 19;10(1):3198. doi: 10.1038/s41467-019-11155-3. Nat Commun. 2019. PMID: 31324776 Free PMC article.

7

Mechanism of Phosphatidylglycerol Activation Catalyzed by Prolipoprotein Diacylglyceryl Transferase.

Singh W, Bilal M, McClory J, Dourado D, Quinn D, Moody TS, Sutcliffe I, Huang M. Singh W, et al. Among authors: huang m. J Phys Chem B. 2019 Aug 22;123(33):7092-7102. doi: 10.1021/acs.jpcb.9b04227. Epub 2019 Aug 7. J Phys Chem B. 2019. PMID: 31340643

8

Reaction Mechanism of Histone Demethylation in αKG-dependent Non-Heme Iron Enzymes.

Singh W, Quinn D, Moody TS, Huang M. Singh W, et al. Among authors: huang m. J Phys Chem B. 2019 Sep 19;123(37):7801-7811. doi: 10.1021/acs.jpcb.9b06064. Epub 2019 Sep 10. J Phys Chem B. 2019. PMID: 31469562

9

The mutagenesis of a single site for enhancing or reversing the enantio- or regiopreference of cyclohexanone monooxygenases.

Hu Y , Xu W , Hui C , Xu J , Huang M , Lin X , Wu Q . Hu Y , et al. Among authors: huang m. Chem Commun (Camb). 2020 Aug 21;56(65):9356-9359. doi: 10.1039/d0cc03721d. Epub 2020 Jul 16. Chem Commun (Camb). 2020. PMID: 32672300

10

Regio- and stereoselectivity in the CYP450_BM3-catalyzed hydroxylation of complex terpenoids: a QM/MM study.

Hui C, Singh W, Quinn D, Li C, Moody TS, Huang M. Hui C, et al. Among authors: huang m. Phys Chem Chem Phys. 2020 Oct 7;22(38):21696-21706. doi: 10.1039/d0cp03083j. Phys Chem Chem Phys. 2020. PMID: 32969450

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