Luedtke RR - Search Results

1

Leveraging a Low-Affinity Diazaspiro Orthosteric Fragment to Reduce Dopamine D₃ Receptor (D₃R) Ligand Promiscuity across Highly Conserved Aminergic G-Protein-Coupled Receptors (GPCRs).

Reilly SW, Riad AA, Hsieh CJ, Sahlholm K, Jacome DA, Griffin S, Taylor M, Weng CC, Xu K, Kirschner N, Luedtke RR, Parry C, Malhotra S, Karanicolas J, Mach RH. Reilly SW, et al. Among authors: luedtke rr. J Med Chem. 2019 May 23;62(10):5132-5147. doi: 10.1021/acs.jmedchem.9b00412. Epub 2019 May 6. J Med Chem. 2019. PMID: 31021617

2

Effect of N-alkylation on the affinities of analogues of spiperone for dopamine D2 and serotonin 5-HT2 receptors.

Mach RH, Jackson JR, Luedtke RR, Ivins KJ, Molinoff PB, Ehrenkaufer RL. Mach RH, et al. Among authors: luedtke rr. J Med Chem. 1992 Feb 7;35(3):423-30. doi: 10.1021/jm00081a002. J Med Chem. 1992. PMID: 1531364

3

Antibodies with high affinity for spiroperidol--II. Cross reactivity with iodobenzamide and domperidone.

Luedtke RR, Bush M, Mach RH, Ehrenkaufer RE, Kung HF, Molinoff PB. Luedtke RR, et al. Mol Immunol. 1990 Jul;27(7):667-77. doi: 10.1016/0161-5890(90)90010-w. Mol Immunol. 1990. PMID: 2395438

4

Genetic polymorphisms at the rat and murine loci coding for dopamine D2-like receptors.

Scott AW, Griffin SA, Luedtke RR. Scott AW, et al. Among authors: luedtke rr. Brain Res Mol Brain Res. 1995 Apr;29(2):347-57. doi: 10.1016/0169-328x(94)00271-f. Brain Res Mol Brain Res. 1995. PMID: 7609622

5

PET imaging studies of dopamine D2 receptors: comparison of [18F]N-methylspiperone and the benzamide analogues [18F]MABN and [18F]MBP in baboon brain.

Mach RH, Ehrenkaufer RL, Greenberg JH, Shao L, Morton TE, Evora PH, Nowak PA, Luedtke RR, Cohen D, Reivich M. Mach RH, et al. Among authors: luedtke rr. Synapse. 1995 Mar;19(3):177-87. doi: 10.1002/syn.890190305. Synapse. 1995. PMID: 7784958

6

18F-labeled benzamides for studying the dopamine D2 receptor with positron emission tomography.

Mach RH, Luedtke RR, Unsworth CD, Boundy VA, Nowak PA, Scripko JG, Elder ST, Jackson JR, Hoffman PL, Evora PH, et al. Mach RH, et al. Among authors: luedtke rr. J Med Chem. 1993 Nov 12;36(23):3707-20. doi: 10.1021/jm00075a028. J Med Chem. 1993. PMID: 8246241

7

The use of [18F]4-fluorobenzyl iodide (FBI) in PET radiotracer synthesis: model alkylation studies and its application in the design of dopamine D1 and D2 receptor-based imaging agents.

Mach RH, Elder ST, Morton TE, Nowak PA, Evora PH, Scripko JG, Luedtke RR, Unsworth CD, Filtz T, Rao AV, et al. Mach RH, et al. Among authors: luedtke rr. Nucl Med Biol. 1993 Aug;20(6):777-94. doi: 10.1016/0969-8051(93)90165-q. Nucl Med Biol. 1993. PMID: 8401379

8

Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes.

Luedtke RR, Griffin SA, Conroy SS, Jin X, Pinto A, Sesack SR. Luedtke RR, et al. J Neuroimmunol. 1999 Nov 15;101(2):170-87. doi: 10.1016/s0165-5728(99)00142-3. J Neuroimmunol. 1999. PMID: 10580800

9

The effects of benzamide analogues on cocaine self-administration in rhesus monkeys.

Nader MA, Green KL, Luedtke RR, Mach RH. Nader MA, et al. Among authors: luedtke rr. Psychopharmacology (Berl). 1999 Nov;147(2):143-52. doi: 10.1007/s002130051154. Psychopharmacology (Berl). 1999. PMID: 10591881

10

Comparison of two fluorine-18 labeled benzamide derivatives that bind reversibly to dopamine D2 receptors: in vitro binding studies and positron emission tomography.

Mach RH, Nader MA, Ehrenkaufer RL, Line SW, Smith CR, Luedtke RR, Kung MP, Kung HF, Lyons D, Morton TE. Mach RH, et al. Among authors: luedtke rr. Synapse. 1996 Dec;24(4):322-33. doi: 10.1002/(SICI)1098-2396(199612)24:4<322::AID-SYN2>3.0.CO;2-F. Synapse. 1996. PMID: 10638823

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