Gheyas F - Search Results

1

Operating characteristics of stepwise covariate selection in pharmacometric modeling.

Ahamadi M, Largajolli A, Diderichsen PM, de Greef R, Kerbusch T, Witjes H, Chawla A, Davis CB, Gheyas F. Ahamadi M, et al. Among authors: gheyas f. J Pharmacokinet Pharmacodyn. 2019 Jun;46(3):273-285. doi: 10.1007/s10928-019-09635-6. Epub 2019 Apr 24. J Pharmacokinet Pharmacodyn. 2019. PMID: 31020450

2

Chronic Administration of Anacetrapib Is Associated With Accumulation in Adipose and Slow Elimination.

Krishna R, Gheyas F, Liu Y, Hagen DR, Walker B, Chawla A, Cote J, Blaustein RO, Gutstein DE. Krishna R, et al. Among authors: gheyas f. Clin Pharmacol Ther. 2017 Nov;102(5):832-840. doi: 10.1002/cpt.700. Epub 2017 May 2. Clin Pharmacol Ther. 2017. PMID: 28380664 Clinical Trial.

3

Leveraging model-informed approaches for drug discovery and development in the cardiovascular space.

Dockendorf MF, Vargo RC, Gheyas F, Chain ASY, Chatterjee MS, Wenning LA. Dockendorf MF, et al. Among authors: gheyas f. J Pharmacokinet Pharmacodyn. 2018 Jun;45(3):355-364. doi: 10.1007/s10928-018-9571-3. Epub 2018 Jan 20. J Pharmacokinet Pharmacodyn. 2018. PMID: 29353335 Free PMC article. Review.

4

A Disease Progression Model to Quantify the Nonmotor Symptoms of Parkinson's Disease in Participants With Leucine-Rich Repeat Kinase 2 Mutation.

Ahamadi M, Mehrotra N, Hanan N, Lai Yee K, Gheyas F, Anton J, Bani M, Boroojerdi B, Smit H, Weidemann J, Macha S, Thuillier V, Chen C, Yang M, Williams-Gray CH, Stebbins GT, Pagano G, Hang Y, Marek K, Venuto CS, Javidnia M, Dexter D, Pedata A, Stafford B, Akalu M, Stephenson D, Romero K, Sinha V; Critical Path for Parkinson’s Consortium. Ahamadi M, et al. Among authors: gheyas f. Clin Pharmacol Ther. 2021 Aug;110(2):508-518. doi: 10.1002/cpt.2277. Epub 2021 Jun 12. Clin Pharmacol Ther. 2021. PMID: 33894056

5

Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice.

Hartmann G, Kumar S, Johns D, Gheyas F, Gutstein D, Shen X, Burton A, Lederman H, Lutz R, Jackson T, Chavez-Eng C, Mitra K. Hartmann G, et al. Among authors: gheyas f. Drug Metab Dispos. 2016 Mar;44(3):428-34. doi: 10.1124/dmd.115.067736. Epub 2015 Dec 28. Drug Metab Dispos. 2016. PMID: 26712818

6

Pharmacokinetics and Pharmacodynamics of Anacetrapib in Black and White Healthy Subjects.

Krishna R, Gheyas F, Corr C, Cote J, Liu Y, Wagner J, Gutstein DE. Krishna R, et al. Among authors: gheyas f. J Clin Pharmacol. 2018 Dec;58(12):1578-1585. doi: 10.1002/jcph.1287. Epub 2018 Jul 20. J Clin Pharmacol. 2018. PMID: 30029292

7

Pharmacokinetics and Pharmacodynamics of Anacetrapib Following Single Doses in Healthy, Young Japanese and White Male Subjects.

Krishna R, Gheyas F, Liu Y, Cote J, Laterza O, Ruckle JL, Wagner JA, Denker AE. Krishna R, et al. Among authors: gheyas f. J Clin Pharmacol. 2018 Feb;58(2):254-262. doi: 10.1002/jcph.1004. Epub 2017 Sep 8. J Clin Pharmacol. 2018. PMID: 28884824 Clinical Trial.

8

Pharmacokinetics, Safety and Tolerability of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein (CETP) Inhibitor, After Single and Multiple Doses in Healthy Chinese Subjects.

Chen H, Chen W, Li H, Xu H, Yuan F, Sheng L, Liu C, Lin P, Yang M, Li X, Liu Y, Walker BM, Gheyas F, Iwamoto M, Stoch SA, Krishna R. Chen H, et al. Among authors: gheyas f. Adv Ther. 2021 Jul;38(7):3973-3985. doi: 10.1007/s12325-021-01794-8. Epub 2021 Jun 8. Adv Ther. 2021. PMID: 34101144

9

Population Pharmacokinetics of Vericiguat in Patients With Heart Failure With Reduced Ejection Fraction: An Integrated Analysis.

Trujillo ME, Arrington L, Patel Y, Passarell J, Wenning L, Blaustein RO, Armstrong PW, Meyer M, Becker C, Gheyas F. Trujillo ME, et al. Among authors: gheyas f. Clin Pharmacol Ther. 2022 Nov;112(5):1061-1069. doi: 10.1002/cpt.2712. Epub 2022 Aug 13. Clin Pharmacol Ther. 2022. PMID: 35841202

10

Effect of Vorapaxar Alone and in Combination with Aspirin on Bleeding Time and Platelet Aggregation in Healthy Adult Subjects.

Kraft WK, Gilmartin JH, Chappell DL, Gheyas F, Walker BM, Nagalla S, Naik UP, Horrow JC, Wrishko RE, Zhang S, Anderson MS. Kraft WK, et al. Among authors: gheyas f. Clin Transl Sci. 2016 Aug;9(4):221-7. doi: 10.1111/cts.12405. Epub 2016 Jun 15. Clin Transl Sci. 2016. PMID: 27304196 Free PMC article. Clinical Trial.

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