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A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease.
Polverino F, Rojas-Quintero J, Wang X, Petersen H, Zhang L, Gai X, Higham A, Zhang D, Gupta K, Rout A, Yambayev I, Pinto-Plata V, Sholl LM, Cunoosamy D, Celli BR, Goldring J, Singh D, Tesfaigzi Y, Wedzicha J, Olsson H, Owen CA. Polverino F, et al. Among authors: zhang l, zhang d. Am J Respir Crit Care Med. 2018 Nov 15;198(10):1254-1267. doi: 10.1164/rccm.201707-1331OC. Am J Respir Crit Care Med. 2018. PMID: 29750543 Free PMC article.
A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD.
Wang X, Polverino F, Rojas-Quintero J, Zhang D, Sánchez J, Yambayev I, Lindqvist E, Virtala R, Djukanovic R, Davies DE, Wilson S, O'Donnell R, Cunoosamy D, Hazon P, Higham A, Singh D, Olsson H, Owen CA. Wang X, et al. Among authors: zhang d. Am J Respir Crit Care Med. 2018 Jun 4;198(12):1500-18. doi: 10.1164/rccm.201711-2300OC. Online ahead of print. Am J Respir Crit Care Med. 2018. PMID: 29864380 Free PMC article.
ADAM15 expression is increased in lung CD8+ T cells, macrophages, and bronchial epithelial cells in patients with COPD and is inversely related to airflow obstruction.
Wang X, Zhang D, Higham A, Wolosianka S, Gai X, Zhou L, Petersen H, Pinto-Plata V, Divo M, Silverman EK, Celli B, Singh D, Sun Y, Owen CA. Wang X, et al. Among authors: zhang d. Respir Res. 2020 Jul 16;21(1):188. doi: 10.1186/s12931-020-01446-5. Respir Res. 2020. PMID: 32677970 Free PMC article.
A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice.
Wang X, Rojas-Quintero J, Zhang D, Nakajima T, Walker KH, Peh HY, Li Y, Fucci QA, Tesfaigzi Y, Owen CA. Wang X, et al. Among authors: zhang d. Mucosal Immunol. 2021 Mar;14(2):342-356. doi: 10.1038/s41385-020-0325-3. Epub 2020 Jul 20. Mucosal Immunol. 2021. PMID: 32690871 Free PMC article.
Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment.
Polverino F, Wu TD, Rojas-Quintero J, Wang X, Mayo J, Tomchaney M, Tram J, Packard S, Zhang D, Cleveland KH, Cordoba-Lanus E, Owen CA, Fawzy A, Kinney GL, Hersh CP, Hansel NN, Doubleday K, Sauler M, Tesfaigzi Y, Ledford JG, Casanova C, Zmijewski J, Konhilas J, Langlais PR, Schnellmann R, Rahman I, McCormack M, Celli B. Polverino F, et al. Among authors: zhang d. Am J Respir Crit Care Med. 2021 Sep 15;204(6):651-666. doi: 10.1164/rccm.202012-4510OC. Am J Respir Crit Care Med. 2021. PMID: 34033525 Free PMC article.
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