Lynch JP - Search Results

1

KLF4 activates NFκB signaling and esophageal epithelial inflammation via the Rho-related GTP-binding protein RHOF.

Shaverdashvili K, Padlo J, Weinblatt D, Jia Y, Jiang W, Rao D, Laczkó D, Whelan KA, Lynch JP, Muir AB, Katz JP. Shaverdashvili K, et al. Among authors: lynch jp. PLoS One. 2019 Apr 18;14(4):e0215746. doi: 10.1371/journal.pone.0215746. eCollection 2019. PLoS One. 2019. PMID: 30998758 Free PMC article.

2

Mechanisms of Barrett's oesophagus: intestinal differentiation, stem cells, and tissue models.

Nakagawa H, Whelan K, Lynch JP. Nakagawa H, et al. Among authors: lynch jp. Best Pract Res Clin Gastroenterol. 2015 Feb;29(1):3-16. doi: 10.1016/j.bpg.2014.11.001. Epub 2014 Nov 12. Best Pract Res Clin Gastroenterol. 2015. PMID: 25743452 Free PMC article. Review.

3

Modeling Esophagitis Using Human Three-Dimensional Organotypic Culture System.

Laczkó D, Wang F, Johnson FB, Jhala N, Rosztóczy A, Ginsberg GG, Falk GW, Rustgi AK, Lynch JP. Laczkó D, et al. Among authors: lynch jp. Am J Pathol. 2017 Aug;187(8):1787-1799. doi: 10.1016/j.ajpath.2017.04.013. Epub 2017 Jun 13. Am J Pathol. 2017. PMID: 28627413 Free PMC article.

4

Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress.

Kong J, Whelan KA, Laczkó D, Dang B, Caro Monroig A, Soroush A, Falcone J, Amaravadi RK, Rustgi AK, Ginsberg GG, Falk GW, Nakagawa H, Lynch JP. Kong J, et al. Among authors: lynch jp. Mol Carcinog. 2016 Nov;55(11):1526-1541. doi: 10.1002/mc.22406. Epub 2015 Sep 16. Mol Carcinog. 2016. PMID: 26373456 Free PMC article.

5

The homeodomain transcription factor Cdx1 does not behave as an oncogene in normal mouse intestine.

Crissey MA, Guo RJ, Fogt F, Li H, Katz JP, Silberg DG, Suh ER, Lynch JP. Crissey MA, et al. Among authors: lynch jp. Neoplasia. 2008 Jan;10(1):8-19. doi: 10.1593/neo.07703. Neoplasia. 2008. PMID: 18231635 Free PMC article.

6

Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4.

Vega ME, Giroux V, Natsuizaka M, Liu M, Klein-Szanto AJ, Stairs DB, Nakagawa H, Wang KK, Wang TC, Lynch JP, Rustgi AK. Vega ME, et al. Among authors: lynch jp. Cell Cycle. 2014;13(24):3857-66. doi: 10.4161/15384101.2014.972875. Cell Cycle. 2014. PMID: 25558829 Free PMC article.

7

Ectopic Cdx2 expression in murine esophagus models an intermediate stage in the emergence of Barrett's esophagus.

Kong J, Crissey MA, Funakoshi S, Kreindler JL, Lynch JP. Kong J, et al. Among authors: lynch jp. PLoS One. 2011 Apr 6;6(4):e18280. doi: 10.1371/journal.pone.0018280. PLoS One. 2011. PMID: 21494671 Free PMC article.

8

Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus.

Stairs DB, Nakagawa H, Klein-Szanto A, Mitchell SD, Silberg DG, Tobias JW, Lynch JP, Rustgi AK. Stairs DB, et al. Among authors: lynch jp. PLoS One. 2008;3(10):e3534. doi: 10.1371/journal.pone.0003534. Epub 2008 Oct 27. PLoS One. 2008. PMID: 18953412 Free PMC article.

9

Cox2 and β-catenin/T-cell factor signaling intestinalize human esophageal keratinocytes when cultured under organotypic conditions.

Kong J, Crissey MA, Stairs DB, Sepulveda AR, Lynch JP. Kong J, et al. Among authors: lynch jp. Neoplasia. 2011 Sep;13(9):792-805. doi: 10.1593/neo.11788. Neoplasia. 2011. PMID: 21969813 Free PMC article.

10

Induction of intestinalization in human esophageal keratinocytes is a multistep process.

Kong J, Nakagawa H, Isariyawongse BK, Funakoshi S, Silberg DG, Rustgi AK, Lynch JP. Kong J, et al. Among authors: lynch jp. Carcinogenesis. 2009 Jan;30(1):122-30. doi: 10.1093/carcin/bgn227. Epub 2008 Oct 8. Carcinogenesis. 2009. PMID: 18845559 Free PMC article.

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