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Page 1
Computational analysis of cancer genome sequencing data.
Cortés-Ciriano I, Gulhan DC, Lee JJ, Melloni GEM, Park PJ. Cortés-Ciriano I, et al. Among authors: melloni gem. Nat Rev Genet. 2022 May;23(5):298-314. doi: 10.1038/s41576-021-00431-y. Epub 2021 Dec 8. Nat Rev Genet. 2022. PMID: 34880424 Review.
Somatic mosaicism reveals clonal distributions of neocortical development.
Breuss MW, Yang X, Schlachetzki JCM, Antaki D, Lana AJ, Xu X, Chung C, Chai G, Stanley V, Song Q, Newmeyer TF, Nguyen A, O'Brien S, Hoeksema MA, Cao B, Nott A, McEvoy-Venneri J, Pasillas MP, Barton ST, Copeland BR, Nahas S, Van Der Kraan L, Ding Y; NIMH Brain Somatic Mosaicism Network; Glass CK, Gleeson JG. Breuss MW, et al. Nature. 2022 Apr;604(7907):689-696. doi: 10.1038/s41586-022-04602-7. Epub 2022 Apr 20. Nature. 2022. PMID: 35444276 Free PMC article.
Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns.
Watson EV, Lee JJ, Gulhan DC, Melloni GEM, Venev SV, Magesh RY, Frederick A, Chiba K, Wooten EC, Naxerova K, Dekker J, Park PJ, Elledge SJ. Watson EV, et al. Among authors: melloni gem. Nat Genet. 2024 May;56(5):900-912. doi: 10.1038/s41588-024-01665-2. Epub 2024 Feb 22. Nat Genet. 2024. PMID: 38388848 Free PMC article.
Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Gilly A, Suveges D, Kuchenbaecker K, Pollard M, Southam L, Hatzikotoulas K, Farmaki AE, Bjornland T, Waples R, Appel EVR, Casalone E, Melloni G, Kilian B, Rayner NW, Ntalla I, Kundu K, Walter K, Danesh J, Butterworth A, Barroso I, Tsafantakis E, Dedoussis G, Moltke I, Zeggini E. Gilly A, et al. Nat Commun. 2018 Nov 7;9(1):4674. doi: 10.1038/s41467-018-07070-8. Nat Commun. 2018. PMID: 30405126 Free PMC article.
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Dellino GI, Palluzzi F, Chiariello AM, Piccioni R, Bianco S, Furia L, De Conti G, Bouwman BAM, Melloni G, Guido D, Giacò L, Luzi L, Cittaro D, Faretta M, Nicodemi M, Crosetto N, Pelicci PG. Dellino GI, et al. Nat Genet. 2019 Jun;51(6):1011-1023. doi: 10.1038/s41588-019-0421-z. Epub 2019 May 20. Nat Genet. 2019. PMID: 31110352
Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Gilly A, Suveges D, Kuchenbaecker K, Pollard M, Southam L, Hatzikotoulas K, Farmaki AE, Bjornland T, Waples R, Appel EVR, Casalone E, Melloni G, Kilian B, Rayner NW, Ntalla I, Kundu K, Walter K, Danesh J, Butterworth A, Barroso I, Tsafantakis E, Dedoussis G, Moltke I, Zeggini E. Gilly A, et al. Nat Commun. 2018 Dec 19;9(1):5460. doi: 10.1038/s41467-018-07730-9. Nat Commun. 2018. PMID: 30568165 Free PMC article.
Very low-depth whole-genome sequencing in complex trait association studies.
Gilly A, Southam L, Suveges D, Kuchenbaecker K, Moore R, Melloni GEM, Hatzikotoulas K, Farmaki AE, Ritchie G, Schwartzentruber J, Danecek P, Kilian B, Pollard MO, Ge X, Tsafantakis E, Dedoussis G, Zeggini E. Gilly A, et al. Among authors: melloni gem. Bioinformatics. 2019 Aug 1;35(15):2555-2561. doi: 10.1093/bioinformatics/bty1032. Bioinformatics. 2019. PMID: 30576415 Free PMC article.
p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value.
Santoro A, Vlachou T, Luzi L, Melloni G, Mazzarella L, D'Elia E, Aobuli X, Pasi CE, Reavie L, Bonetti P, Punzi S, Casoli L, Sabò A, Moroni MC, Dellino GI, Amati B, Nicassio F, Lanfrancone L, Pelicci PG. Santoro A, et al. Cell Rep. 2019 Jan 15;26(3):624-638.e8. doi: 10.1016/j.celrep.2018.12.071. Cell Rep. 2019. PMID: 30650356 Free PMC article.
37 results