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An unexpected N-terminal loop in PD-1 dominates binding by nivolumab.
Tan S, Zhang H, Chai Y, Song H, Tong Z, Wang Q, Qi J, Wong G, Zhu X, Liu WJ, Gao S, Wang Z, Shi Y, Yang F, Gao GF, Yan J. Tan S, et al. Among authors: gao s, gao gf. Nat Commun. 2017 Feb 6;8:14369. doi: 10.1038/ncomms14369. Nat Commun. 2017. PMID: 28165004 Free PMC article.
Transcriptional Regulation of the Warburg Effect in Cancer by SIX1.
Li L, Liang Y, Kang L, Liu Y, Gao S, Chen S, Li Y, You W, Dong Q, Hong T, Yan Z, Jin S, Wang T, Zhao W, Mai H, Huang J, Han X, Ji Q, Song Q, Yang C, Zhao S, Xu X, Ye Q. Li L, et al. Among authors: gao s. Cancer Cell. 2018 Mar 12;33(3):368-385.e7. doi: 10.1016/j.ccell.2018.01.010. Epub 2018 Feb 15. Cancer Cell. 2018. PMID: 29455928 Free article.
PES1 is a critical component of telomerase assembly and regulates cellular senescence.
Cheng L, Yuan B, Ying S, Niu C, Mai H, Guan X, Yang X, Teng Y, Lin J, Huang J, Jin R, Wu J, Liu B, Chang S, Wang E, Zhang C, Hou N, Cheng X, Xu D, Yang X, Gao S, Ye Q. Cheng L, et al. Among authors: gao s. Sci Adv. 2019 May 15;5(5):eaav1090. doi: 10.1126/sciadv.aav1090. eCollection 2019 May. Sci Adv. 2019. PMID: 31106266 Free PMC article.
Tumor cell-intrinsic PD-1 receptor is a tumor suppressor and mediates resistance to PD-1 blockade therapy.
Wang X, Yang X, Zhang C, Wang Y, Cheng T, Duan L, Tong Z, Tan S, Zhang H, Saw PE, Gu Y, Wang J, Zhang Y, Shang L, Liu Y, Jiang S, Yan B, Li R, Yang Y, Yu J, Chen Y, Gao GF, Ye Q, Gao S. Wang X, et al. Among authors: gao s, gao gf. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6640-6650. doi: 10.1073/pnas.1921445117. Epub 2020 Mar 11. Proc Natl Acad Sci U S A. 2020. PMID: 32161124 Free PMC article.
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