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Page 1
Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegaly.
Chenlo M, Rodriguez-Gomez IA, Serramito R, Garcia-Rendueles AR, Villar-Taibo R, Fernandez-Rodriguez E, Perez-Romero S, Suarez-Fariña M, Garcia-Allut A, Cabezas-Agricola JM, Rodriguez-Garcia J, Lear PV, Alvarez-San Martin RM, Alvarez-Escola C, Bernabeu I, Alvarez CV. Chenlo M, et al. Among authors: lear pv. EBioMedicine. 2019 May;43:537-552. doi: 10.1016/j.ebiom.2019.04.007. Epub 2019 Apr 8. EBioMedicine. 2019. PMID: 30975543 Free PMC article.
Review of novel aspects of the regulation of ghrelin secretion.
Al Massadi O, Lear PV, Muller TD, Lopez M, Dieguez C, Tschop MH, Nogueiras R. Al Massadi O, et al. Among authors: lear pv. Curr Drug Metab. 2014;15(4):398-413. doi: 10.2174/1389200215666140505153723. Curr Drug Metab. 2014. PMID: 24813425 Review.
Increased expression of fatty-acid and calcium metabolism genes in failing human heart.
García-Rúa V, Otero MF, Lear PV, Rodríguez-Penas D, Feijóo-Bandín S, Noguera-Moreno T, Calaza M, Álvarez-Barredo M, Mosquera-Leal A, Parrington J, Brugada J, Portolés M, Rivera M, González-Juanatey JR, Lago F. García-Rúa V, et al. Among authors: lear pv. PLoS One. 2012;7(6):e37505. doi: 10.1371/journal.pone.0037505. Epub 2012 Jun 6. PLoS One. 2012. PMID: 22701570 Free PMC article.
Absence of intracellular ion channels TPC1 and TPC2 leads to mature-onset obesity in male mice, due to impaired lipid availability for thermogenesis in brown adipose tissue.
Lear PV, González-Touceda D, Porteiro Couto B, Viaño P, Guymer V, Remzova E, Tunn R, Chalasani A, García-Caballero T, Hargreaves IP, Tynan PW, Christian HC, Nogueiras R, Parrington J, Diéguez C. Lear PV, et al. Endocrinology. 2015 Mar;156(3):975-86. doi: 10.1210/en.2014-1766. Epub 2014 Dec 29. Endocrinology. 2015. PMID: 25545384 Free PMC article.
Metabolic alterations derived from absence of Two-Pore Channel 1 at cardiac level.
Garcia-Rua V, Feijoo-Bandin S, Garcia-Vence M, Aragon-Herrera A, Bravo SB, Rodriguez-Penas D, Mosquera-Leal A, Lear PV, Parrington J, Alonso J, Rosello-Lleti E, Portoles M, Rivera M, Gonzalez-Juanatey JR, Lago F. Garcia-Rua V, et al. Among authors: lear pv. J Biosci. 2016 Dec;41(4):643-658. doi: 10.1007/s12038-016-9647-4. J Biosci. 2016. PMID: 27966485
The brain: a new organ for the metabolic actions of SIRT1.
Al Massadi O, Quiñones M, Lear P, Dieguez C, Nogueiras R. Al Massadi O, et al. Horm Metab Res. 2013 Dec;45(13):960-6. doi: 10.1055/s-0033-1351322. Epub 2013 Aug 15. Horm Metab Res. 2013. PMID: 23950036 Review.
Endolysosomal two-pore channels regulate autophagy in cardiomyocytes.
García-Rúa V, Feijóo-Bandín S, Rodríguez-Penas D, Mosquera-Leal A, Abu-Assi E, Beiras A, María Seoane L, Lear P, Parrington J, Portolés M, Roselló-Lletí E, Rivera M, Gualillo O, Parra V, Hill JA, Rothermel B, González-Juanatey JR, Lago F. García-Rúa V, et al. J Physiol. 2016 Jun 1;594(11):3061-77. doi: 10.1113/JP271332. Epub 2016 Feb 4. J Physiol. 2016. PMID: 26757341 Free PMC article.
24 results