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MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer.
McCoy P, Mangiola S, Macintyre G, Hutchinson R, Tran B, Pope B, Georgeson P, Hong MKH, Kurganovs N, Lunke S, Clarkson MJ, Cmero M, Kerger M, Stuchbery R, Chow K, Haviv I, Ryan A, Costello AJ, Corcoran NM, Hovens CM. McCoy P, et al. Among authors: kerger m. Prostate Cancer Prostatic Dis. 2021 Dec;24(4):1167-1180. doi: 10.1038/s41391-021-00379-4. Epub 2021 Jun 9. Prostate Cancer Prostatic Dis. 2021. PMID: 34108644
Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression.
Mangiola S, McCoy P, Modrak M, Souza-Fonseca-Guimaraes F, Blashki D, Stuchbery R, Keam SP, Kerger M, Chow K, Nasa C, Le Page M, Lister N, Monard S, Peters J, Dundee P, Williams SG, Costello AJ, Neeson PJ, Pal B, Huntington ND, Corcoran NM, Papenfuss AT, Hovens CM. Mangiola S, et al. Among authors: kerger m. BMC Cancer. 2021 Jul 22;21(1):846. doi: 10.1186/s12885-021-08529-6. BMC Cancer. 2021. PMID: 34294073 Free PMC article.
Loss of SNAI2 in Prostate Cancer Correlates With Clinical Response to Androgen Deprivation Therapy.
Cmero M, Kurganovs NJ, Stuchbery R, McCoy P, Grima C, Ngyuen A, Chow K, Mangiola S, Macintyre G, Howard N, Kerger M, Dundee P, Ruljancich P, Clarke D, Grummet J, Peters JS, Costello AJ, Norden S, Ryan A, Parente P, Hovens CM, Corcoran NM. Cmero M, et al. Among authors: kerger m. JCO Precis Oncol. 2021 Jun 22;5:PO.20.00337. doi: 10.1200/PO.20.00337. eCollection 2021 Jun. JCO Precis Oncol. 2021. PMID: 34322653 Free PMC article. Clinical Trial.
Phase 2 Study of Neoadjuvant FGFR Inhibition and Androgen Deprivation Therapy Prior to Prostatectomy.
Liow E, Howard N, Jung CH, Pope B, Campbell BK, Nguyen A, Kerger M, Ruddle JB, Anton A, Thomas B, Chu K, Dundee P, Peters JS, Costello AJ, Ryan AS, Hovens CM, Tran B, Corcoran NM. Liow E, et al. Among authors: kerger m. Clin Genitourin Cancer. 2022 Oct;20(5):452-458. doi: 10.1016/j.clgc.2022.05.007. Epub 2022 May 18. Clin Genitourin Cancer. 2022. PMID: 35688680 Clinical Trial.
Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer.
Hong MK, Macintyre G, Wedge DC, Van Loo P, Patel K, Lunke S, Alexandrov LB, Sloggett C, Cmero M, Marass F, Tsui D, Mangiola S, Lonie A, Naeem H, Sapre N, Phal PM, Kurganovs N, Chin X, Kerger M, Warren AY, Neal D, Gnanapragasam V, Rosenfeld N, Pedersen JS, Ryan A, Haviv I, Costello AJ, Corcoran NM, Hovens CM. Hong MK, et al. Among authors: kerger m. Nat Commun. 2015 Apr 1;6:6605. doi: 10.1038/ncomms7605. Nat Commun. 2015. PMID: 25827447 Free PMC article.
Detection of ctDNA in plasma of patients with clinically localised prostate cancer is associated with rapid disease progression.
Lau E, McCoy P, Reeves F, Chow K, Clarkson M, Kwan EM, Packwood K, Northen H, He M, Kingsbury Z, Mangiola S, Kerger M, Furrer MA, Crowe H, Costello AJ, McBride DJ, Ross MT, Pope B, Hovens CM, Corcoran NM. Lau E, et al. Among authors: kerger m. Genome Med. 2020 Aug 17;12(1):72. doi: 10.1186/s13073-020-00770-1. Genome Med. 2020. PMID: 32807235 Free PMC article.
19 results