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Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment.
Gullbo J, Fryknäs M, Rickardson L, Darcy P, Hägg M, Wickström M, Hassan S, Westman G, Brnjic S, Nygren P, Linder S, Larsson R. Gullbo J, et al. Among authors: linder s. Biochem Pharmacol. 2011 Jul 15;82(2):139-47. doi: 10.1016/j.bcp.2011.04.003. Epub 2011 Apr 22. Biochem Pharmacol. 2011. PMID: 21531212 Free article.
The phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 is effective in inhibiting regrowth of tumour cells after cytotoxic therapy.
Hernlund E, Olofsson MH, Fayad W, Fryknäs M, Lesiak-Mieczkowska K, Zhang X, Brnjic S, Schmidt V, D'Arcy P, Sjöblom T, De Milito A, Larsson R, Linder S. Hernlund E, et al. Among authors: linder s. Eur J Cancer. 2012 Feb;48(3):396-406. doi: 10.1016/j.ejca.2011.11.013. Epub 2011 Dec 7. Eur J Cancer. 2012. PMID: 22154651
Proteasome deubiquitinases as novel targets for cancer therapy.
D'Arcy P, Linder S. D'Arcy P, et al. Among authors: linder s. Int J Biochem Cell Biol. 2012 Nov;44(11):1729-38. doi: 10.1016/j.biocel.2012.07.011. Epub 2012 Jul 20. Int J Biochem Cell Biol. 2012. PMID: 22819849 Review.
Combining [11C]-AnxA5 PET imaging with serum biomarkers for improved detection in live mice of modest cell death in human solid tumor xenografts.
Cheng Q, Lu L, Grafström J, Olofsson MH, Thorell JO, Samén E, Johansson K, Ahlzén HS, Stone-Elander S, Linder S, Arnér ES; Sel-tag Imaging Project. Cheng Q, et al. Among authors: linder s. PLoS One. 2012;7(8):e42151. doi: 10.1371/journal.pone.0042151. Epub 2012 Aug 1. PLoS One. 2012. PMID: 22870292 Free PMC article.
Site-specifically 11C-labeled Sel-tagged annexin A5 and a size-matched control for dynamic in vivo PET imaging of protein distribution in tissues prior to and after induced cell death.
Cheng Q, Lu L, Grafström J, Olofsson MH, Thorell JO, Samén E, Johansson K, Ahlzén HS, Linder S, Arnér ES, Stone-Elander S. Cheng Q, et al. Among authors: linder s. Biochim Biophys Acta. 2013 Mar;1830(3):2562-73. doi: 10.1016/j.bbagen.2012.12.007. Biochim Biophys Acta. 2013. PMID: 23262140 Free article.
701 results