BRD4 inhibition impairs DNA mismatch repair, induces mismatch repair mutation signatures and creates therapeutic vulnerability to immune checkpoint blockade in MMR-proficient tumors.
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Fu Y, et al. Among authors: yang b.
J Immunother Cancer. 2023 Apr;11(4):e006070. doi: 10.1136/jitc-2022-006070.
J Immunother Cancer. 2023.
PMID: 37072347
Free PMC article.