DeGregori J - Search Results

1

Targeting Glutamine Metabolism and Redox State for Leukemia Therapy.

Gregory MA, Nemkov T, Park HJ, Zaberezhnyy V, Gehrke S, Adane B, Jordan CT, Hansen KC, D'Alessandro A, DeGregori J. Gregory MA, et al. Among authors: degregori j. Clin Cancer Res. 2019 Jul 1;25(13):4079-4090. doi: 10.1158/1078-0432.CCR-18-3223. Epub 2019 Apr 2. Clin Cancer Res. 2019. PMID: 30940653 Free PMC article.

2

Irradiation alters selection for oncogenic mutations in hematopoietic progenitors.

Marusyk A, Casás-Selves M, Henry CJ, Zaberezhnyy V, Klawitter J, Christians U, DeGregori J. Marusyk A, et al. Among authors: degregori j. Cancer Res. 2009 Sep 15;69(18):7262-9. doi: 10.1158/0008-5472.CAN-09-0604. Epub 2009 Sep 8. Cancer Res. 2009. PMID: 19738065 Free PMC article.

3

Irradiation selects for p53-deficient hematopoietic progenitors.

Marusyk A, Porter CC, Zaberezhnyy V, DeGregori J. Marusyk A, et al. Among authors: degregori j. PLoS Biol. 2010 Mar 2;8(3):e1000324. doi: 10.1371/journal.pbio.1000324. PLoS Biol. 2010. PMID: 20208998 Free PMC article.

4

Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.

Gregory MA, Phang TL, Neviani P, Alvarez-Calderon F, Eide CA, O'Hare T, Zaberezhnyy V, Williams RT, Druker BJ, Perrotti D, Degregori J. Gregory MA, et al. Among authors: degregori j. Cancer Cell. 2010 Jul 13;18(1):74-87. doi: 10.1016/j.ccr.2010.04.025. Cancer Cell. 2010. PMID: 20609354 Free PMC article.

5

Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis.

Henry CJ, Marusyk A, Zaberezhnyy V, Adane B, DeGregori J. Henry CJ, et al. Among authors: degregori j. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21713-8. doi: 10.1073/pnas.1005486107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098275 Free PMC article.

6

Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia.

Porter CC, Kim J, Fosmire S, Gearheart CM, van Linden A, Baturin D, Zaberezhnyy V, Patel PR, Gao D, Tan AC, DeGregori J. Porter CC, et al. Among authors: degregori j. Leukemia. 2012 Jun;26(6):1266-76. doi: 10.1038/leu.2011.392. Epub 2012 Jan 13. Leukemia. 2012. PMID: 22289989 Free PMC article.

7

Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition.

Casás-Selves M, Kim J, Zhang Z, Helfrich BA, Gao D, Porter CC, Scarborough HA, Bunn PA Jr, Chan DC, Tan AC, DeGregori J. Casás-Selves M, et al. Among authors: degregori j. Cancer Res. 2012 Aug 15;72(16):4154-64. doi: 10.1158/0008-5472.CAN-11-2848. Epub 2012 Jun 27. Cancer Res. 2012. PMID: 22738915 Free PMC article.

8

Using functional genomics to overcome therapeutic resistance in hematological malignancies.

Alvarez-Calderon F, Gregory MA, DeGregori J. Alvarez-Calderon F, et al. Among authors: degregori j. Immunol Res. 2013 Mar;55(1-3):100-15. doi: 10.1007/s12026-012-8353-z. Immunol Res. 2013. PMID: 22941562 Free PMC article. Review.

9

Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.

Spreafico A, Tentler JJ, Pitts TM, Tan AC, Gregory MA, Arcaroli JJ, Klauck PJ, McManus MC, Hansen RJ, Kim J, Micel LN, Selby HM, Newton TP, McPhillips KL, Gustafson DL, Degregori JV, Messersmith WA, Winn RA, Eckhardt SG. Spreafico A, et al. Among authors: degregori jv. Clin Cancer Res. 2013 Aug 1;19(15):4149-62. doi: 10.1158/1078-0432.CCR-12-3140. Epub 2013 Jun 11. Clin Cancer Res. 2013. PMID: 23757356 Free PMC article.

10

Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia.

Gardner LA, Klawitter J, Gregory MA, Zaberezhnyy V, Baturin D, Pollyea DA, Takebe N, Christians U, Gore L, DeGregori J, Porter CC. Gardner LA, et al. Among authors: degregori j. Am J Hematol. 2014 Sep;89(9):896-903. doi: 10.1002/ajh.23776. Epub 2014 Jun 19. Am J Hematol. 2014. PMID: 24891015 Free PMC article. Clinical Trial.

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