Henin E - Search Results

1

Prediction of Human Nonlinear Pharmacokinetics of a New Bcl-2 Inhibitor Using PBPK Modeling and Interspecies Extrapolation Strategy.

Pierrillas PB, Henin E, Ball K, Ogier J, Amiel M, Kraus-Berthier L, Chenel M, Bouzom F, Tod M. Pierrillas PB, et al. Among authors: henin e. Drug Metab Dispos. 2019 Jun;47(6):648-656. doi: 10.1124/dmd.118.085605. Epub 2019 Apr 2. Drug Metab Dispos. 2019. PMID: 30940629

2

Tumor Growth Inhibition Modelling Based on Receptor Occupancy and Biomarker Activity of a New Bcl-2 Inhibitor in Mice.

Pierrillas PB, Henin E, Ogier J, Kraus-Berthier L, Chenel M, Bouzom F, Tod M. Pierrillas PB, et al. Among authors: henin e. J Pharmacol Exp Ther. 2018 Dec;367(3):414-424. doi: 10.1124/jpet.118.251694. Epub 2018 Sep 18. J Pharmacol Exp Ther. 2018. PMID: 30228112

3

Translational approach from preclinical to clinical: comparison of dose finding methods of a new Bcl2 inhibitor using PK-PD modeling and interspecies extrapolation.

Pierrillas PB, Henin E, Ogier J, Amiel M, Kraus-Berthier L, Chenel M, Bouzom F, Tod M. Pierrillas PB, et al. Among authors: henin e. Invest New Drugs. 2020 Dec;38(6):1796-1806. doi: 10.1007/s10637-020-00953-y. Epub 2020 May 25. Invest New Drugs. 2020. PMID: 32451663

4

Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: a Novel Method to Handle the Interval Censoring Caused by Measurement of Smaller Tumors.

Pierrillas PB, Tod M, Amiel M, Chenel M, Henin E. Pierrillas PB, et al. Among authors: henin e. AAPS J. 2016 Mar;18(2):404-15. doi: 10.1208/s12248-015-9862-1. Epub 2016 Jan 12. AAPS J. 2016. PMID: 26757730 Free PMC article.

5

Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: Handling Sacrifice Censoring and Error Caused by Experimental Measurement on Larger Tumor Sizes.

Pierrillas PB, Tod M, Amiel M, Chenel M, Henin E. Pierrillas PB, et al. Among authors: henin e. AAPS J. 2016 Sep;18(5):1262-1272. doi: 10.1208/s12248-016-9936-8. Epub 2016 Jun 21. AAPS J. 2016. PMID: 27329303

6

Pharmacokinetic interactions in mice between irinotecan and MBL-II-141, an ABCG2 inhibitor.

Hénin E, Honorat M, Guitton J, Di Pietro A, Payen L, Tod M. Hénin E, et al. Biopharm Drug Dispos. 2017 Jul;38(5):351-362. doi: 10.1002/bdd.2069. Epub 2017 Mar 23. Biopharm Drug Dispos. 2017. PMID: 28207160

7

Pharmacokinetically based estimation of patient compliance with oral anticancer chemotherapies: in silico evaluation.

Hénin E, Tod M, Trillet-Lenoir V, Rioufol C, Tranchand B, Girard P. Hénin E, et al. Clin Pharmacokinet. 2009;48(6):359-69. doi: 10.2165/00003088-200948060-00002. Clin Pharmacokinet. 2009. PMID: 19650675

8

Prediction of tumour response induced by chemotherapy using modelling of CA-125 kinetics in recurrent ovarian cancer patients.

Wilbaux M, Hénin E, Oza A, Colomban O, Pujade-Lauraine E, Freyer G, Tod M, You B. Wilbaux M, et al. Among authors: henin e. Br J Cancer. 2014 Mar 18;110(6):1517-24. doi: 10.1038/bjc.2014.75. Epub 2014 Feb 20. Br J Cancer. 2014. PMID: 24556626 Free PMC article. Clinical Trial.

9

Dynamic modeling in ovarian cancer: an original approach linking early changes in modeled longitudinal CA-125 kinetics and survival to help decisions in early drug development.

Wilbaux M, Hénin E, Oza A, Colomban O, Pujade-Lauraine E, Freyer G, Tod M, You B. Wilbaux M, et al. Among authors: henin e. Gynecol Oncol. 2014 Jun;133(3):460-6. doi: 10.1016/j.ygyno.2014.04.003. Epub 2014 Apr 12. Gynecol Oncol. 2014. PMID: 24726614 Clinical Trial.

10

Dose adaptation of capecitabine based on individual prediction of limiting toxicity grade: evaluation by clinical trial simulation.

Paule I, Tod M, Hénin E, You B, Freyer G, Girard P. Paule I, et al. Among authors: henin e. Cancer Chemother Pharmacol. 2012 Feb;69(2):447-55. doi: 10.1007/s00280-011-1714-9. Epub 2011 Aug 2. Cancer Chemother Pharmacol. 2012. PMID: 21809035

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