Chenel M - Search Results

1

Prediction of Human Nonlinear Pharmacokinetics of a New Bcl-2 Inhibitor Using PBPK Modeling and Interspecies Extrapolation Strategy.

Pierrillas PB, Henin E, Ball K, Ogier J, Amiel M, Kraus-Berthier L, Chenel M, Bouzom F, Tod M. Pierrillas PB, et al. Among authors: chenel m. Drug Metab Dispos. 2019 Jun;47(6):648-656. doi: 10.1124/dmd.118.085605. Epub 2019 Apr 2. Drug Metab Dispos. 2019. PMID: 30940629

2

Drug-drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: application to midazolam and a phase I compound. Part 2: clinical trial results.

Chenel M, Bouzom F, Cazade F, Ogungbenro K, Aarons L, Mentré F. Chenel M, et al. J Pharmacokinet Pharmacodyn. 2008 Dec;35(6):661-81. doi: 10.1007/s10928-008-9105-5. Epub 2009 Jan 7. J Pharmacokinet Pharmacodyn. 2008. PMID: 19130187 Free PMC article.

3

Drug-drug interaction predictions with PBPK models and optimal multiresponse sampling time designs: application to midazolam and a phase I compound. Part 1: comparison of uniresponse and multiresponse designs using PopDes.

Chenel M, Bouzom F, Aarons L, Ogungbenro K. Chenel M, et al. J Pharmacokinet Pharmacodyn. 2008 Dec;35(6):635-59. doi: 10.1007/s10928-008-9104-6. Epub 2009 Jan 7. J Pharmacokinet Pharmacodyn. 2008. PMID: 19130188

4

Predictions of metabolic drug-drug interactions using physiologically based modelling: Two cytochrome P450 3A4 substrates coadministered with ketoconazole or verapamil.

Perdaems N, Blasco H, Vinson C, Chenel M, Whalley S, Cazade F, Bouzom F. Perdaems N, et al. Among authors: chenel m. Clin Pharmacokinet. 2010 Apr;49(4):239-58. doi: 10.2165/11318130-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20214408

5

Model-based approaches for ivabradine development in paediatric population, part I: study preparation assessment.

Peigné S, Bouzom F, Brendel K, Gesson C, Fouliard S, Chenel M. Peigné S, et al. Among authors: chenel m. J Pharmacokinet Pharmacodyn. 2016 Feb;43(1):13-27. doi: 10.1007/s10928-015-9451-z. Epub 2015 Nov 12. J Pharmacokinet Pharmacodyn. 2016. PMID: 26563503

6

Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: a Novel Method to Handle the Interval Censoring Caused by Measurement of Smaller Tumors.

Pierrillas PB, Tod M, Amiel M, Chenel M, Henin E. Pierrillas PB, et al. Among authors: chenel m. AAPS J. 2016 Mar;18(2):404-15. doi: 10.1208/s12248-015-9862-1. Epub 2016 Jan 12. AAPS J. 2016. PMID: 26757730 Free PMC article.

7

Improvement of Parameter Estimations in Tumor Growth Inhibition Models on Xenografted Animals: Handling Sacrifice Censoring and Error Caused by Experimental Measurement on Larger Tumor Sizes.

Pierrillas PB, Tod M, Amiel M, Chenel M, Henin E. Pierrillas PB, et al. Among authors: chenel m. AAPS J. 2016 Sep;18(5):1262-1272. doi: 10.1208/s12248-016-9936-8. Epub 2016 Jun 21. AAPS J. 2016. PMID: 27329303

8

Prediction of renal transporter-mediated drug-drug interactions for a drug which is an OAT substrate and inhibitor using PBPK modelling.

Ball K, Jamier T, Parmentier Y, Denizot C, Mallier A, Chenel M. Ball K, et al. Among authors: chenel m. Eur J Pharm Sci. 2017 Aug 30;106:122-132. doi: 10.1016/j.ejps.2017.05.055. Epub 2017 May 25. Eur J Pharm Sci. 2017. PMID: 28552429

9

Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology.

Pierrillas PB, Fouliard S, Chenel M, Hooker AC, Friberg LE, Karlsson MO. Pierrillas PB, et al. Among authors: chenel m. AAPS J. 2018 Mar 7;20(2):39. doi: 10.1208/s12248-018-0206-9. AAPS J. 2018. PMID: 29516207

10

Correction to: Model-Based Adaptive Optimal Design (MBAOD) Improves Combination Dose Finding Designs: an Example in Oncology.

Pierrillas PB, Fouliard S, Chenel M, Hooker AC, Friberg LE, Karlsson MO. Pierrillas PB, et al. Among authors: chenel m. AAPS J. 2018 Mar 27;20(3):55. doi: 10.1208/s12248-018-0218-5. AAPS J. 2018. PMID: 29589158

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