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Residual microglia following short-term PLX5622 treatment in 5xFAD mice exhibit diminished NLRP3 inflammasome and mTOR signaling, and enhanced autophagy.
Kodali M, Madhu LN, Somayaji Y, Attaluri S, Huard C, Panda PK, Shankar G, Rao S, Shuai B, Gonzalez JJ, Oake C, Hering C, Babu RS, Kotian S, Shetty AK. Kodali M, et al. Among authors: huard c. Aging Cell. 2024 Nov 21:e14398. doi: 10.1111/acel.14398. Online ahead of print. Aging Cell. 2024. PMID: 39571180 Free article.
Residual Microglia Following Short-term PLX5622 Treatment in 5xFAD Mice Exhibit Diminished NLRP3 Inflammasome and mTOR Signaling, and Enhanced Autophagy.
Kodali M, Madhu LN, Somayaji Y, Attaluri S, Huard C, Panda PK, Shankar G, Rao S, Shuai B, Gonzalez JJ, Oake C, Hering C, Babu RS, Kotian S, Shetty AK. Kodali M, et al. Among authors: huard c. bioRxiv [Preprint]. 2024 Jul 16:2024.07.11.603157. doi: 10.1101/2024.07.11.603157. bioRxiv. 2024. Update in: Aging Cell. 2024 Nov 21:e14398. doi: 10.1111/acel.14398 PMID: 39071343 Free PMC article. Updated. Preprint.
The anticancer potential of the CLK kinases inhibitors 1C8 and GPS167 revealed by their impact on the epithelial-mesenchymal transition and the antiviral immune response.
Shkreta L, Toutant J, Delannoy A, Durantel D, Salvetti A, Ehresmann S, Sauvageau M, Delbrouck JA, Gravel-Trudeau A, Comeau C, Huard C, Coulombe-Huntington J, Tyers M, Grierson D, Boudreault PL, Chabot B. Shkreta L, et al. Among authors: huard c. Oncotarget. 2024 May 16;15:313-325. doi: 10.18632/oncotarget.28585. Oncotarget. 2024. PMID: 38753413 Free PMC article.
Clinical validation of C12FDG as a marker associated with senescence and osteoarthritic phenotypes.
Hambright WS, Duke VR, Goff AD, Goff AW, Minas LT, Kloser H, Gao X, Huard C, Guo P, Lu A, Mitchell J, Mullen M, Su C, Tchkonia T, Espindola Netto JM, Robbins PD, Niedernhofer LJ, Kirkland JL, Bahney CS, Philippon M, Huard J. Hambright WS, et al. Among authors: huard c. Aging Cell. 2024 May;23(5):e14113. doi: 10.1111/acel.14113. Epub 2024 May 6. Aging Cell. 2024. PMID: 38708778 Free PMC article.
Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition.
Wilson GA, Vuina K, Sava G, Huard C, Meneguello L, Coulombe-Huntington J, Bertomeu T, Maizels RJ, Lauring J, Kriston-Vizi J, Tyers M, Ali S, Bertoli C, de Bruin RAM. Wilson GA, et al. Among authors: huard c. Mol Cell. 2023 Nov 16;83(22):4078-4092.e6. doi: 10.1016/j.molcel.2023.10.017. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977119 Free article.
75 results