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Detecting differential peaks in ChIP-seq signals with ODIN.
Allhoff M, Seré K, Chauvistré H, Lin Q, Zenke M, Costa IG. Allhoff M, et al. Among authors: costa ig. Bioinformatics. 2014 Dec 15;30(24):3467-75. doi: 10.1093/bioinformatics/btu722. Epub 2014 Nov 3. Bioinformatics. 2014. PMID: 25371479
Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites.
Hänzelmann S, Beier F, Gusmao EG, Koch CM, Hummel S, Charapitsa I, Joussen S, Benes V, Brümmendorf TH, Reid G, Costa IG, Wagner W. Hänzelmann S, et al. Among authors: costa ig. Clin Epigenetics. 2015 Mar 4;7(1):19. doi: 10.1186/s13148-015-0057-5. eCollection 2015. Clin Epigenetics. 2015. PMID: 25763115 Free PMC article.
Mtss1 is a critical epigenetically regulated tumor suppressor in CML.
Schemionek M, Herrmann O, Reher MM, Chatain N, Schubert C, Costa IG, Hänzelmann S, Gusmao EG, Kintsler S, Braunschweig T, Hamilton A, Helgason GV, Copland M, Schwab A, Müller-Tidow C, Li S, Holyoake TL, Brümmendorf TH, Koschmieder S. Schemionek M, et al. Among authors: costa ig. Leukemia. 2016 Apr;30(4):823-32. doi: 10.1038/leu.2015.329. Epub 2015 Dec 1. Leukemia. 2016. PMID: 26621336 Free article.
JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation.
Czech J, Cordua S, Weinbergerova B, Baumeister J, Crepcia A, Han L, Maié T, Costa IG, Denecke B, Maurer A, Schubert C, Feldberg K, Gezer D, Brümmendorf TH, Müller-Newen G, Mayer J, Racil Z, Kubesova B, Knudsen T, Sørensen AL, Holmström M, Kjær L, Skov V, Larsen TS, Hasselbalch HC, Chatain N, Koschmieder S. Czech J, et al. Among authors: costa ig. Leukemia. 2019 Apr;33(4):995-1010. doi: 10.1038/s41375-018-0295-6. Epub 2018 Nov 23. Leukemia. 2019. PMID: 30470838
Stem cell persistence in CML is mediated by extrinsically activated JAK1-STAT3 signaling.
Kuepper MK, Bütow M, Herrmann O, Ziemons J, Chatain N, Maurer A, Kirschner M, Maié T, Costa IG, Eschweiler J, Koschmieder S, Brümmendorf TH, Müller-Newen G, Schemionek M. Kuepper MK, et al. Among authors: costa ig. Leukemia. 2019 Aug;33(8):1964-1977. doi: 10.1038/s41375-019-0427-7. Epub 2019 Mar 6. Leukemia. 2019. PMID: 30842608
153 results