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Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells in Phenotypic Screening: A Transforming Growth Factor-β Type 1 Receptor Kinase Inhibitor Induces Efficient Cardiac Differentiation.
Drowley L, Koonce C, Peel S, Jonebring A, Plowright AT, Kattman SJ, Andersson H, Anson B, Swanson BJ, Wang QD, Brolen G. Drowley L, et al. Stem Cells Transl Med. 2016 Feb;5(2):164-74. doi: 10.5966/sctm.2015-0114. Epub 2015 Dec 18. Stem Cells Transl Med. 2016. PMID: 26683871 Free PMC article.
Comparative transcriptomic analysis identifies genes differentially expressed in human epicardial progenitors and hiPSC-derived cardiac progenitors.
Synnergren J, Drowley L, Plowright AT, Brolén G, Goumans MJ, Gittenberger-de Groot AC, Sartipy P, Wang QD. Synnergren J, et al. Among authors: drowley l. Physiol Genomics. 2016 Nov 1;48(11):771-784. doi: 10.1152/physiolgenomics.00064.2016. Epub 2016 Sep 2. Physiol Genomics. 2016. PMID: 27591124 Free article.
Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts.
Paunovic AI, Drowley L, Nordqvist A, Ericson E, Mouchet E, Jonebring A, Grönberg G, Kvist AJ, Engkvist O, Brown MR, Gedda K, Goumans MJ, Wang QD, Plowright AT. Paunovic AI, et al. Among authors: drowley l. ACS Chem Biol. 2017 Jan 20;12(1):132-141. doi: 10.1021/acschembio.6b00683. Epub 2016 Nov 30. ACS Chem Biol. 2017. PMID: 28103692
High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets.
Woo LA, Tkachenko S, Ding M, Plowright AT, Engkvist O, Andersson H, Drowley L, Barrett I, Firth M, Akerblad P, Wolf MJ, Bekiranov S, Brautigan DL, Wang QD, Saucerman JJ. Woo LA, et al. Among authors: drowley l. J Mol Cell Cardiol. 2019 Feb;127:204-214. doi: 10.1016/j.yjmcc.2018.12.015. Epub 2018 Dec 28. J Mol Cell Cardiol. 2019. PMID: 30597148 Free PMC article.
Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway.
Mills RJ, Parker BL, Quaife-Ryan GA, Voges HK, Needham EJ, Bornot A, Ding M, Andersson H, Polla M, Elliott DA, Drowley L, Clausen M, Plowright AT, Barrett IP, Wang QD, James DE, Porrello ER, Hudson JE. Mills RJ, et al. Among authors: drowley l. Cell Stem Cell. 2019 Jun 6;24(6):895-907.e6. doi: 10.1016/j.stem.2019.03.009. Epub 2019 Mar 28. Cell Stem Cell. 2019. PMID: 30930147 Free article.
Discovery of retinoic acid receptor agonists as proliferators of cardiac progenitor cells through a phenotypic screening approach.
Drowley L, McPheat J, Nordqvist A, Peel S, Karlsson U, Martinsson S, Müllers E, Dellsén A, Knight S, Barrett I, Sánchez J, Magnusson B, Greber B, Wang QD, Plowright AT. Drowley L, et al. Stem Cells Transl Med. 2020 Jan;9(1):47-60. doi: 10.1002/sctm.19-0069. Epub 2019 Sep 11. Stem Cells Transl Med. 2020. PMID: 31508905 Free PMC article.
21 results