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Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK).
Watterson SH, Liu Q, Beaudoin Bertrand M, Batt DG, Li L, Pattoli MA, Skala S, Cheng L, Obermeier MT, Moore R, Yang Z, Vickery R, Elzinga PA, Discenza L, D'Arienzo C, Gillooly KM, Taylor TL, Pulicicchio C, Zhang Y, Heimrich E, McIntyre KW, Ruan Q, Westhouse RA, Catlett IM, Zheng N, Chaudhry C, Dai J, Galella MA, Tebben AJ, Pokross M, Li J, Zhao R, Smith D, Rampulla R, Allentoff A, Wallace MA, Mathur A, Salter-Cid L, Macor JE, Carter PH, Fura A, Burke JR, Tino JA. Watterson SH, et al. Among authors: moore r. J Med Chem. 2019 Apr 11;62(7):3228-3250. doi: 10.1021/acs.jmedchem.9b00167. Epub 2019 Mar 29. J Med Chem. 2019. PMID: 30893553
Quantification of Linrodostat and its metabolites: Overcoming bioanalytical challenges in support of a discovery Indoleamine 2,3 dioxygenase program.
Discenza LN, Balog A, Huang C, Moore R, Ranasinghe A, Lin TA, D'Arienzo C, Olah TV. Discenza LN, et al. Among authors: moore r. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Sep 1;1207:123305. doi: 10.1016/j.jchromb.2022.123305. Epub 2022 Jun 28. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35839627
Clinical Manifestations.
Weinstein AM, Rothenberger S, Moore RC, Snitz BE, Cohen AD, Butters MA. Weinstein AM, et al. Among authors: moore rc. Alzheimers Dement. 2024 Dec;20 Suppl 3:e090464. doi: 10.1002/alz.090464. Alzheimers Dement. 2024. PMID: 39750490
Clinical Manifestations.
Moore RC, Kuehn K, Khullar D, Jantz C, Song JM, Padmanabham P, Mausbach B, Martin JL, Song Y. Moore RC, et al. Alzheimers Dement. 2024 Dec;20 Suppl 3:e091422. doi: 10.1002/alz.091422. Alzheimers Dement. 2024. PMID: 39750486
Persistent Short Sleep Duration From Pregnancy to 2 to 7 Years After Delivery and Metabolic Health.
Kim M, Wiener LE, Gilbert J, McNeil RB, Reid KJ, Grobman WA, Facco F, Haas DM, Silver RM, Greenland P, Yee LM, Zee PC; Eunice Kennedy Shriver National Institute of Child Health and Human Development NuMoM2b and National Heart, Lung, and Blood Institute NuMoM2b Heart Health Study Network. Kim M, et al. JAMA Netw Open. 2024 Dec 2;7(12):e2452204. doi: 10.1001/jamanetworkopen.2024.52204. JAMA Netw Open. 2024. PMID: 39724370 Free PMC article.
8,386 results