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In vitro analyses of suspected arrhythmogenic thin filament variants as a cause of sudden cardiac death in infants.
Shafaattalab S, Li AY, Lin E, Stevens CM, Dewar LJ, Lynn FC, Sanatani S, Laksman Z, Morin RD, van Petegem F, Hove-Madsen L, Tieleman DP, Davis JP, Tibbits GF. Shafaattalab S, et al. Among authors: lynn fc. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6969-6974. doi: 10.1073/pnas.1819023116. Epub 2019 Mar 18. Proc Natl Acad Sci U S A. 2019. PMID: 30886088 Free PMC article.
A versatile fluorescence-quenched substrate for quantitative measurement of glucocerebrosidase activity within live cells.
Deen MC, Zhu Y, Gros C, Na N, Gilormini PA, Shen DL, Bhosale S, Anastasi N, Wang R, Shan X, Harde E, Jagasia R, Lynn FC, Vocadlo DJ. Deen MC, et al. Among authors: lynn fc. Proc Natl Acad Sci U S A. 2022 Jul 19;119(29):e2200553119. doi: 10.1073/pnas.2200553119. Epub 2022 Jul 12. Proc Natl Acad Sci U S A. 2022. PMID: 35858317 Free PMC article.
Calcium-dependent transcriptional changes in human pancreatic islet cells reveal functional diversity in islet cell subtypes.
Yoon JS, Sasaki S, Velghe J, Lee MYY, Winata H, Nian C, Lynn FC. Yoon JS, et al. Among authors: lynn fc. Diabetologia. 2022 Sep;65(9):1519-1533. doi: 10.1007/s00125-022-05718-1. Epub 2022 May 26. Diabetologia. 2022. Retraction in: Diabetologia. 2023 Nov;66(11):2186. doi: 10.1007/s00125-023-05983-8 PMID: 35616696 Free PMC article. Retracted.
Lrrc55 is a novel prosurvival factor in pancreatic islets.
Makkar G, Shrivastava V, Hlavay B, Pretorius M, Kyle BD, Braun AP, Lynn FC, Huang C. Makkar G, et al. Among authors: lynn fc. Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E794-E804. doi: 10.1152/ajpendo.00028.2019. Epub 2019 Sep 17. Am J Physiol Endocrinol Metab. 2019. PMID: 31526288 Free PMC article.
Transcriptional coactivator MED15 is required for beta cell maturation.
Kadhim AZ, Vanderkruk B, Mar S, Dan M, Zosel K, Xu EE, Spencer RJ, Sasaki S, Cheng X, Sproul SLJ, Speckmann T, Nian C, Cullen R, Shi R, Luciani DS, Hoffman BG, Taubert S, Lynn FC. Kadhim AZ, et al. Among authors: lynn fc. Nat Commun. 2024 Oct 8;15(1):8711. doi: 10.1038/s41467-024-52801-9. Nat Commun. 2024. PMID: 39379383 Free PMC article.
Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans.
Shomer N, Kadhim AZ, Grants JM, Cheng X, Alhusari D, Bhanshali F, Poon AF, Lee MYY, Muhuri A, Park JI, Shih J, Lee D, Lee SV, Lynn FC, Taubert S. Shomer N, et al. Among authors: lynn fc. PLoS Genet. 2019 Dec 9;15(12):e1008508. doi: 10.1371/journal.pgen.1008508. eCollection 2019 Dec. PLoS Genet. 2019. PMID: 31815936 Free PMC article.
84 results