Yang K - Search Results

1

Synthesis, mitochondrial localization of fluorescent derivatives of cinnamamide as anticancer agents.

Yang K, Li Y, Tang Q, Zheng L, He D. Yang K, et al. Eur J Med Chem. 2019 May 15;170:45-54. doi: 10.1016/j.ejmech.2019.03.001. Epub 2019 Mar 9. Eur J Med Chem. 2019. PMID: 30878831

2

Synthesis of mitochondria-targeted coumarin-3-carboxamide fluorescent derivatives: Inhibiting mitochondrial TrxR2 and cell proliferation on breast cancer cells.

Li Y, Tang Q, Xie Y, He D, Yang K, Zheng L. Li Y, et al. Among authors: yang k. Bioorg Med Chem Lett. 2021 Feb 1;33:127750. doi: 10.1016/j.bmcl.2020.127750. Epub 2020 Dec 21. Bioorg Med Chem Lett. 2021. PMID: 33340662

3

Target ROS to induce apoptosis and cell cycle arrest by 5,7-dimethoxy-1,4-naphthoquinone derivative.

Li K, Wang B, Zheng L, Yang K, Li Y, Hu M, He D. Li K, et al. Among authors: yang k. Bioorg Med Chem Lett. 2018 Feb 1;28(3):273-277. doi: 10.1016/j.bmcl.2017.12.059. Epub 2017 Dec 26. Bioorg Med Chem Lett. 2018. PMID: 29305189

4

Anti-acute myeloid leukemia activity of 2-chloro-3-alkyl-1,4-naphthoquinone derivatives through inducing mtDNA damage and GSH depletion.

Li K, Yang K, Zheng L, Li Y, Wang Q, Lin R, He D. Li K, et al. Among authors: yang k. Bioorg Med Chem. 2018 Aug 7;26(14):4191-4200. doi: 10.1016/j.bmc.2018.07.010. Epub 2018 Jul 7. Bioorg Med Chem. 2018. PMID: 30007564

5

Four copper(II) compounds synthesized by anion regulation: Structure, anticancer function and anticancer mechanism.

Zhang Z, Gou Y, Wang J, Yang K, Qi J, Zhou Z, Liang S, Liang H, Yang F. Zhang Z, et al. Among authors: yang f, yang k. Eur J Med Chem. 2016 Oct 4;121:399-409. doi: 10.1016/j.ejmech.2016.05.021. Epub 2016 May 14. Eur J Med Chem. 2016. PMID: 27309677

6

Developing Anticancer Ferric Prodrugs Based on the N-Donor Residues of Human Serum Albumin Carrier IIA Subdomain.

Qi J, Gou Y, Zhang Y, Yang K, Chen S, Liu L, Wu X, Wang T, Zhang W, Yang F. Qi J, et al. Among authors: yang f, yang k. J Med Chem. 2016 Aug 25;59(16):7497-511. doi: 10.1021/acs.jmedchem.6b00509. Epub 2016 Aug 8. J Med Chem. 2016. PMID: 27441502

7

Discovery and biological evaluation of tanshinone derivatives as potent dual inhibitors of indoleamine 2, 3-dioxygenase 1 and tryptophan 2, 3-dioxygenase.

Liu J, Ren J, Yang K, Chen S, Yang X, Zhao QS. Liu J, et al. Among authors: yang k, yang x. Eur J Med Chem. 2022 May 5;235:114294. doi: 10.1016/j.ejmech.2022.114294. Epub 2022 Mar 16. Eur J Med Chem. 2022. PMID: 35358772

8

Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism.

Liu J, Wu XD, Li W, Yuan Z, Yang K, Zhao QS. Liu J, et al. Among authors: yang k. Bioorg Chem. 2021 Jul;112:104963. doi: 10.1016/j.bioorg.2021.104963. Epub 2021 May 5. Bioorg Chem. 2021. PMID: 33991836

9

Terpyridine copper(II) complexes as potential anticancer agents by inhibiting cell proliferation, blocking the cell cycle and inducing apoptosis in BEL-7402 cells.

Gu YQ, Zhong YJ, Hu MQ, Li HQ, Yang K, Dong Q, Liang H, Chen ZF. Gu YQ, et al. Among authors: yang k. Dalton Trans. 2022 Feb 1;51(5):1968-1978. doi: 10.1039/d1dt02988f. Dalton Trans. 2022. PMID: 35023532

10

Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.

Huddle BC, Grimley E, Buchman CD, Chtcherbinine M, Debnath B, Mehta P, Yang K, Morgan CA, Li S, Felton J, Sun D, Mehta G, Neamati N, Buckanovich RJ, Hurley TD, Larsen SD. Huddle BC, et al. Among authors: yang k. J Med Chem. 2018 Oct 11;61(19):8754-8773. doi: 10.1021/acs.jmedchem.8b00930. Epub 2018 Sep 28. J Med Chem. 2018. PMID: 30221940 Free PMC article.

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