Niu T - Search Results

1

Design, synthesis and evaluation of novel 7H-pyrrolo[2,3-d]pyrimidin-4-amine derivatives as potent, selective and reversible Bruton's tyrosine kinase (BTK) inhibitors for the treatment of rheumatoid arthritis.

Zhang C, Pei H, He J, Zhu J, Li W, Niu T, Xiang M, Chen L. Zhang C, et al. Among authors: niu t. Eur J Med Chem. 2019 May 1;169:121-143. doi: 10.1016/j.ejmech.2019.02.077. Epub 2019 Mar 6. Eur J Med Chem. 2019. PMID: 30875504

2

[Antitumor effects of matrix protein of vesicular stomatic virus on EL4 lymphoma mice].

Lin SJ, Yu QM, Meng WT, Wen YJ, Chen LJ, Niu T. Lin SJ, et al. Among authors: niu t. Sichuan Da Xue Xue Bao Yi Xue Ban. 2011 Mar;42(2):213-7. Sichuan Da Xue Xue Bao Yi Xue Ban. 2011. PMID: 21500556 Chinese.

3

Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer.

Yang Z, Wang T, Wang F, Niu T, Liu Z, Chen X, Long C, Tang M, Cao D, Wang X, Xiang W, Yi Y, Ma L, You J, Chen L. Yang Z, et al. Among authors: niu t. J Med Chem. 2016 Feb 25;59(4):1455-70. doi: 10.1021/acs.jmedchem.5b01342. Epub 2015 Oct 13. J Med Chem. 2016. PMID: 26443078

4

SKLB-677, an FLT3 and Wnt/β-catenin signaling inhibitor, displays potent activity in models of FLT3-driven AML.

Ma S, Yang LL, Niu T, Cheng C, Zhong L, Zheng MW, Xiong Y, Li LL, Xiang R, Chen LJ, Zhou Q, Wei YQ, Yang SY. Ma S, et al. Among authors: niu t. Sci Rep. 2015 Oct 26;5:15646. doi: 10.1038/srep15646. Sci Rep. 2015. PMID: 26497577 Free PMC article.

5

Development of Purine-Based Hydroxamic Acid Derivatives: Potent Histone Deacetylase Inhibitors with Marked in Vitro and in Vivo Antitumor Activities.

Chen Y, Wang X, Xiang W, He L, Tang M, Wang F, Wang T, Yang Z, Yi Y, Wang H, Niu T, Zheng L, Lei L, Li X, Song H, Chen L. Chen Y, et al. Among authors: niu t. J Med Chem. 2016 Jun 9;59(11):5488-504. doi: 10.1021/acs.jmedchem.6b00579. Epub 2016 May 24. J Med Chem. 2016. PMID: 27186676

6

SKLB-23bb, A HDAC6-Selective Inhibitor, Exhibits Superior and Broad-Spectrum Antitumor Activity via Additionally Targeting Microtubules.

Wang F, Zheng L, Yi Y, Yang Z, Qiu Q, Wang X, Yan W, Bai P, Yang J, Li D, Pei H, Niu T, Ye H, Nie C, Hu Y, Yang S, Wei Y, Chen L. Wang F, et al. Among authors: niu t. Mol Cancer Ther. 2018 Apr;17(4):763-775. doi: 10.1158/1535-7163.MCT-17-0332. Mol Cancer Ther. 2018. PMID: 29610282

7

Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.

Li Y, Xiong Y, Zhang G, Zhang L, Yang W, Yang J, Huang L, Qiao Z, Miao Z, Lin G, Sun Q, Niu T, Chen L, Niu D, Li L, Yang S. Li Y, et al. Among authors: niu t, niu d. J Med Chem. 2018 Dec 27;61(24):11398-11414. doi: 10.1021/acs.jmedchem.8b01652. Epub 2018 Dec 10. J Med Chem. 2018. PMID: 30480444

8

Correction to Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.

Li Y, Xiong Y, Zhang G, Zhang L, Yang W, Yang J, Huang L, Qiao Z, Miao Z, Lin G, Sun Q, Niu T, Chen L, Niu D, Li L, Yang S. Li Y, et al. Among authors: niu t, niu d. J Med Chem. 2019 Mar 28;62(6):3169. doi: 10.1021/acs.jmedchem.9b00368. Epub 2019 Mar 7. J Med Chem. 2019. PMID: 30843694 No abstract available.

9

Identification of Pyrrolo[2,3- d]pyrimidine-Based Derivatives as Potent and Orally Effective Fms-like Tyrosine Receptor Kinase 3 (FLT3) Inhibitors for Treating Acute Myelogenous Leukemia.

Yuan X, Chen Y, Zhang W, He J, Lei L, Tang M, Liu J, Li M, Dou C, Yang T, Yang L, Yang S, Wei Y, Peng A, Niu T, Xiang M, Ye H, Chen L. Yuan X, et al. Among authors: niu t. J Med Chem. 2019 Apr 25;62(8):4158-4173. doi: 10.1021/acs.jmedchem.9b00223. Epub 2019 Apr 15. J Med Chem. 2019. PMID: 30939008

10

Anti-Tumor Study of H6, a 4-Substituted Coumarins Derivative, Loaded Biodegradable Self-Assembly Nano-Micelles In Vitro and In Vivo.

Zhu Z, Su Z, Yang J, Liu H, Tang M, Hu Q, Bai P, Wen J, He J, Niu T, Chen L. Zhu Z, et al. Among authors: niu t. J Biomed Nanotechnol. 2019 Jul 1;15(7):1515-1531. doi: 10.1166/jbn.2019.2797. J Biomed Nanotechnol. 2019. PMID: 31196355

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