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Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5.
Giuliano S, Dufies M, Ndiaye PD, Viotti J, Borchiellini D, Parola J, Vial V, Cormerais Y, Ohanna M, Imbert V, Chamorey E, Rioux-Leclercq N, Savina A, Ferrero JM, Mograbi B, Pagès G. Giuliano S, et al. Among authors: imbert v. Theranostics. 2019 Jan 30;9(4):1181-1199. doi: 10.7150/thno.29093. eCollection 2019. Theranostics. 2019. PMID: 30867824 Free PMC article.
Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS).
Ohanna M, Giuliano S, Bonet C, Imbert V, Hofman V, Zangari J, Bille K, Robert C, Bressac-de Paillerets B, Hofman P, Rocchi S, Peyron JF, Lacour JP, Ballotti R, Bertolotto C. Ohanna M, et al. Among authors: imbert v. Genes Dev. 2011 Jun 15;25(12):1245-61. doi: 10.1101/gad.625811. Epub 2011 Jun 6. Genes Dev. 2011. PMID: 21646373 Free PMC article.
GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin's B lymphomas via NF-κB-dependent induction of HIF-1α.
Chiche J, Pommier S, Beneteau M, Mondragón L, Meynet O, Zunino B, Mouchotte A, Verhoeyen E, Guyot M, Pagès G, Mounier N, Imbert V, Colosetti P, Goncalvès D, Marchetti S, Brière J, Carles M, Thieblemont C, Ricci JE. Chiche J, et al. Among authors: imbert v. Leukemia. 2015 May;29(5):1163-76. doi: 10.1038/leu.2014.324. Epub 2014 Nov 14. Leukemia. 2015. PMID: 25394713
The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.
Rosilio C, Lounnas N, Nebout M, Imbert V, Hagenbeek T, Spits H, Asnafi V, Pontier-Bres R, Reverso J, Michiels JF, Sahra IB, Bost F, Peyron JF. Rosilio C, et al. Among authors: imbert v. Cancer Lett. 2013 Aug 9;336(1):114-26. doi: 10.1016/j.canlet.2013.04.015. Epub 2013 Apr 21. Cancer Lett. 2013. PMID: 23612073
53 results