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Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation.
Sukhanova A, Gorin A, Serebriiskii IG, Gabitova L, Zheng H, Restifo D, Egleston BL, Cunningham D, Bagnyukova T, Liu H, Nikonova A, Adams GP, Zhou Y, Yang DH, Mehra R, Burtness B, Cai KQ, Klein-Szanto A, Kratz LE, Kelley RI, Weiner LM, Herman GE, Golemis EA, Astsaturov I. Sukhanova A, et al. Among authors: liu h. Cancer Discov. 2013 Jan;3(1):96-111. doi: 10.1158/2159-8290.CD-12-0031. Epub 2012 Nov 2. Cancer Discov. 2013. PMID: 23125191 Free PMC article.
Network analysis identifies an HSP90-central hub susceptible in ovarian cancer.
Liu H, Xiao F, Serebriiskii IG, O'Brien SW, Maglaty MA, Astsaturov I, Litwin S, Martin LP, Proia DA, Golemis EA, Connolly DC. Liu H, et al. Clin Cancer Res. 2013 Sep 15;19(18):5053-67. doi: 10.1158/1078-0432.CCR-13-1115. Epub 2013 Jul 30. Clin Cancer Res. 2013. PMID: 23900136 Free PMC article.
Ciliary signalling in cancer.
Liu H, Kiseleva AA, Golemis EA. Liu H, et al. Nat Rev Cancer. 2018 Aug;18(8):511-524. doi: 10.1038/s41568-018-0023-6. Nat Rev Cancer. 2018. PMID: 29802351 Free PMC article. Review.
Cellular Senescence-Inducing Small Molecules for Cancer Treatment.
Liu P, Lu Z, Wu Y, Shang D, Zhao Z, Shen Y, Zhang Y, Zhu F, Liu H, Tu Z. Liu P, et al. Among authors: liu h. Curr Cancer Drug Targets. 2019;19(2):109-119. doi: 10.2174/1568009618666180530092825. Curr Cancer Drug Targets. 2019. PMID: 29848278 Review.
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