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IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study.
Brehm C, Huenecke S, Quaiser A, Esser R, Bremm M, Kloess S, Soerensen J, Kreyenberg H, Seidl C, Becker PS, Mühl H, Klingebiel T, Bader P, Passweg JR, Schwabe D, Koehl U. Brehm C, et al. Among authors: bader p. PLoS One. 2011;6(11):e27351. doi: 10.1371/journal.pone.0027351. Epub 2011 Nov 9. PLoS One. 2011. PMID: 22096557 Free PMC article. Clinical Trial.
Cytotoxic Capacity of IL-15-Stimulated Cytokine-Induced Killer Cells Against Human Acute Myeloid Leukemia and Rhabdomyosarcoma in Humanized Preclinical Mouse Models.
Rettinger E, Meyer V, Kreyenberg H, Volk A, Kuçi S, Willasch A, Koscielniak E, Fulda S, Wels WS, Boenig H, Klingebiel T, Bader P. Rettinger E, et al. Among authors: bader p. Front Oncol. 2012 Apr 9;2:32. doi: 10.3389/fonc.2012.00032. eCollection 2012. Front Oncol. 2012. PMID: 22655268 Free PMC article.
Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol.
Koehl U, Brehm C, Huenecke S, Zimmermann SY, Kloess S, Bremm M, Ullrich E, Soerensen J, Quaiser A, Erben S, Wunram C, Gardlowski T, Auth E, Tonn T, Seidl C, Meyer-Monard S, Stern M, Passweg J, Klingebiel T, Bader P, Schwabe D, Esser R. Koehl U, et al. Among authors: bader p. Front Oncol. 2013 May 17;3:118. doi: 10.3389/fonc.2013.00118. eCollection 2013. Front Oncol. 2013. PMID: 23730623 Free PMC article.
Immunomagnetic selection or irradiation eliminates alloreactive cells but also reduces anti-tumor potential of cytokine-induced killer cells: implications for unmanipulated cytokine-induced killer cell infusion.
Rettinger E, Kreyenberg H, Merker M, Kuçi S, Willasch A, Bug G, Ullrich E, Wels WS, Bonig H, Klingebiel T, Bader P. Rettinger E, et al. Among authors: bader p. Cytotherapy. 2014 Jun;16(6):835-44. doi: 10.1016/j.jcyt.2014.01.003. Epub 2014 Feb 28. Cytotherapy. 2014. PMID: 24582456
Interleukin-2-stimulated natural killer cells are less susceptible to mycophenolate mofetil than non-activated NK cells: possible consequences for immunotherapy.
Brehm C, Huenecke S, Esser R, Kloess S, Quaiser A, Betz S, Zimmermann O, Soerensen J, Passweg JR, Klingebiel T, Schwabe D, Bader P, Koehl U. Brehm C, et al. Among authors: bader p. Cancer Immunol Immunother. 2014 Aug;63(8):821-33. doi: 10.1007/s00262-014-1556-5. Epub 2014 May 8. Cancer Immunol Immunother. 2014. PMID: 24806448 Free PMC article. Clinical Trial.
SMAC Mimetic BV6 Enables Sensitization of Resistant Tumor Cells but also Affects Cytokine-Induced Killer (CIK) Cells: A Potential Challenge for Combination Therapy.
Rettinger E, Glatthaar A, Abhari BA, Oelsner S, Pfirrmann V, Huenecke S, Kuçi S, Kreyenberg H, Willasch AM, Klingebiel T, Fulda S, Bader P. Rettinger E, et al. Among authors: bader p. Front Pediatr. 2014 Jul 18;2:75. doi: 10.3389/fped.2014.00075. eCollection 2014. Front Pediatr. 2014. PMID: 25101252 Free PMC article.
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