Ohkawa Y - Search Results

1

Elucidation of the enigma of glycosphingolipids in the regulation of inflammation and degeneration - Great progress over the last 70 years.

Furukawa K, Ohmi Y, Kondo Y, Bhuiyan RH, Tajima O, Zhang P, Ohkawa Y, Furukawa K. Furukawa K, et al. Among authors: ohkawa y. Proc Jpn Acad Ser B Phys Biol Sci. 2019;95(3):136-149. doi: 10.2183/pjab.95.011. Proc Jpn Acad Ser B Phys Biol Sci. 2019. PMID: 30853699 Free PMC article. Review.

2

Focal adhesion kinase as well as p130Cas and paxillin is crucially involved in the enhanced malignant properties under expression of ganglioside GD3 in melanoma cells.

Hamamura K, Tsuji M, Ohkawa Y, Nakashima H, Miyazaki S, Urano T, Yamamoto N, Ueda M, Furukawa K, Furukawa K. Hamamura K, et al. Among authors: ohkawa y. Biochim Biophys Acta. 2008 Mar;1780(3):513-9. doi: 10.1016/j.bbagen.2007.11.002. Epub 2007 Nov 19. Biochim Biophys Acta. 2008. PMID: 18078823

3

Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21.

Furukawa K, Aixinjueluo W, Kasama T, Ohkawa Y, Yoshihara M, Ohmi Y, Tajima O, Suzumura A, Kittaka D, Furukawa K. Furukawa K, et al. Among authors: ohkawa y. J Neurochem. 2008 May;105(3):1057-66. doi: 10.1111/j.1471-4159.2008.05232.x. Epub 2008 Jan 14. J Neurochem. 2008. PMID: 18194438 Free PMC article.

4

Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3.

Ohkawa Y, Miyazaki S, Miyata M, Hamamura K, Furukawa K, Furukawa K. Ohkawa Y, et al. Biochem Biophys Res Commun. 2008 Aug 15;373(1):14-9. doi: 10.1016/j.bbrc.2008.05.149. Epub 2008 Jun 4. Biochem Biophys Res Commun. 2008. PMID: 18538130

5

Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues.

Ohmi Y, Tajima O, Ohkawa Y, Mori A, Sugiura Y, Furukawa K, Furukawa K. Ohmi Y, et al. Among authors: ohkawa y. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22405-10. doi: 10.1073/pnas.0912336106. Epub 2009 Dec 11. Proc Natl Acad Sci U S A. 2009. PMID: 20018737 Free PMC article.

6

Ganglioside GD3 enhances adhesion signals and augments malignant properties of melanoma cells by recruiting integrins to glycolipid-enriched microdomains.

Ohkawa Y, Miyazaki S, Hamamura K, Kambe M, Miyata M, Tajima O, Ohmi Y, Yamauchi Y, Furukawa K, Furukawa K. Ohkawa Y, et al. J Biol Chem. 2010 Aug 27;285(35):27213-27223. doi: 10.1074/jbc.M109.087791. Epub 2010 Jun 25. J Biol Chem. 2010. PMID: 20581115 Free PMC article.

7

[Drug discovery sciences in Japan with focus on molecular-targeted drugs].

Furukawa K, Hamamura K, Ohkawa Y, Furukawa K. Furukawa K, et al. Among authors: ohkawa y. Nihon Rinsho. 2010 Oct;68(10):1797-802. Nihon Rinsho. 2010. PMID: 20954320 Review. Japanese.

8

[Molecular complex in the vicinity of cell membrane generating cancer phenotypes].

Furukawa K, Hamamura K, Ohkawa Y, Nakashima H, Zhang Q, Furukawa K. Furukawa K, et al. Among authors: ohkawa y. Tanpakushitsu Kakusan Koso. 2008 Sep;53(12 Suppl):1547-51. Tanpakushitsu Kakusan Koso. 2008. PMID: 21089364 Review. Japanese. No abstract available.

9

Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice.

Ohmi Y, Tajima O, Ohkawa Y, Yamauchi Y, Sugiura Y, Furukawa K, Furukawa K. Ohmi Y, et al. Among authors: ohkawa y. J Neurochem. 2011 Mar;116(5):926-35. doi: 10.1111/j.1471-4159.2010.07067.x. Epub 2011 Jan 12. J Neurochem. 2011. PMID: 21214571 Free article.

10

Functional activation of Src family kinase yes protein is essential for the enhanced malignant properties of human melanoma cells expressing ganglioside GD3.

Hamamura K, Tsuji M, Hotta H, Ohkawa Y, Takahashi M, Shibuya H, Nakashima H, Yamauchi Y, Hashimoto N, Hattori H, Ueda M, Furukawa K, Furukawa K. Hamamura K, et al. Among authors: ohkawa y. J Biol Chem. 2011 May 27;286(21):18526-37. doi: 10.1074/jbc.M110.164798. Epub 2011 Mar 31. J Biol Chem. 2011. PMID: 21454696 Free PMC article.

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