Semple KM - Search Results

1

BLT-Immune Humanized Mice as a Model for Nivolumab-Induced Immune-Mediated Adverse Events: Comparison of the NOG and NOG-EXL Strains.

Weaver JL, Zadrozny LM, Gabrielson K, Semple KM, Shea KI, Howard KE. Weaver JL, et al. Among authors: semple km. Toxicol Sci. 2019 May 1;169(1):194-208. doi: 10.1093/toxsci/kfz045. Toxicol Sci. 2019. PMID: 30850839

2

Evaluation of the Ability of Immune Humanized Mice to Demonstrate CD20-Specific Cytotoxicity Induced by Ofatumumab.

Semple KM, Gonzaléz CM, Zarr M, Austin JR, Patel V, Howard KE. Semple KM, et al. Clin Transl Sci. 2019 May;12(3):283-290. doi: 10.1111/cts.12613. Epub 2019 Feb 27. Clin Transl Sci. 2019. PMID: 30737892 Free PMC article.

3

Bone marrow-liver-thymus (BLT) immune humanized mice as a model to predict cytokine release syndrome.

Yan H, Semple KM, Gonzaléz CM, Howard KE. Yan H, et al. Among authors: semple km. Transl Res. 2019 Aug;210:43-56. doi: 10.1016/j.trsl.2019.04.007. Epub 2019 Apr 22. Transl Res. 2019. PMID: 31082370

4

Drug-induced allergic hepatitis develops in mice when myeloid-derived suppressor cells are depleted prior to halothane treatment.

Chakraborty M, Fullerton AM, Semple K, Chea LS, Proctor WR, Bourdi M, Kleiner DE, Zeng X, Ryan PM, Dagur PK, Berkson JD, Reilly TP, Pohl LR. Chakraborty M, et al. Hepatology. 2015 Aug;62(2):546-57. doi: 10.1002/hep.27764. Epub 2015 Mar 25. Hepatology. 2015. PMID: 25712247 Free PMC article.

5

Eosinophils mediate the pathogenesis of halothane-induced liver injury in mice.

Proctor WR, Chakraborty M, Chea LS, Morrison JC, Berkson JD, Semple K, Bourdi M, Pohl LR. Proctor WR, et al. Hepatology. 2013 May;57(5):2026-36. doi: 10.1002/hep.26196. Epub 2013 Mar 15. Hepatology. 2013. PMID: 23238640 Free PMC article.

6

Thymic stromal lymphopoietin and interleukin-4 mediate the pathogenesis of halothane-induced liver injury in mice.

Proctor WR, Chakraborty M, Fullerton AM, Korrapati MC, Ryan PM, Semple K, Morrison JC, Berkson JD, Chea LS, Yang Q, Li AP, Spolski R, West EE, Rochman Y, Leonard WJ, Bourdi M, Pohl LR. Proctor WR, et al. Hepatology. 2014 Nov;60(5):1741-52. doi: 10.1002/hep.27169. Epub 2014 May 20. Hepatology. 2014. PMID: 24723460 Free PMC article.

7

HY-Specific Induced Regulatory T Cells Display High Specificity and Efficacy in the Prevention of Acute Graft-versus-Host Disease.

Li J, Heinrichs J, Haarberg K, Semple K, Veerapathran A, Liu C, Anasetti C, Yu XZ. Li J, et al. J Immunol. 2015 Jul 15;195(2):717-25. doi: 10.4049/jimmunol.1401250. Epub 2015 Jun 5. J Immunol. 2015. PMID: 26048147 Free PMC article.

8

Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice.

Li J, Heinrichs J, Leconte J, Haarberg K, Semple K, Liu C, Gigoux M, Kornete M, Piccirillo CA, Suh WK, Yu XZ. Li J, et al. J Immunol. 2013 Jul 1;191(1):200-7. doi: 10.4049/jimmunol.1203485. Epub 2013 May 31. J Immunol. 2013. PMID: 23729441 Free PMC article.

9

Prevention of GVHD while sparing GVL effect by targeting Th1 and Th17 transcription factor T-bet and RORγt in mice.

Yu Y, Wang D, Liu C, Kaosaard K, Semple K, Anasetti C, Yu XZ. Yu Y, et al. Blood. 2011 Nov 3;118(18):5011-20. doi: 10.1182/blood-2011-03-340315. Epub 2011 Aug 19. Blood. 2011. PMID: 21856864 Free PMC article.

10

Roles of CD28, CTLA4, and inducible costimulator in acute graft-versus-host disease in mice.

Li J, Semple K, Suh WK, Liu C, Chen F, Blazar BR, Yu XZ. Li J, et al. Biol Blood Marrow Transplant. 2011 Jul;17(7):962-9. doi: 10.1016/j.bbmt.2011.01.018. Epub 2011 Mar 27. Biol Blood Marrow Transplant. 2011. PMID: 21447398 Free PMC article.

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