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Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron.
Cedernaes J, Huang W, Ramsey KM, Waldeck N, Cheng L, Marcheva B, Omura C, Kobayashi Y, Peek CB, Levine DC, Dhir R, Awatramani R, Bradfield CA, Wang XA, Takahashi JS, Mokadem M, Ahima RS, Bass J. Cedernaes J, et al. Among authors: kobayashi y. Cell Metab. 2019 May 7;29(5):1078-1091.e5. doi: 10.1016/j.cmet.2019.01.023. Epub 2019 Feb 28. Cell Metab. 2019. PMID: 30827863 Free PMC article.
Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis.
Ramsey KM, Yoshino J, Brace CS, Abrassart D, Kobayashi Y, Marcheva B, Hong HK, Chong JL, Buhr ED, Lee C, Takahashi JS, Imai S, Bass J. Ramsey KM, et al. Among authors: kobayashi y. Science. 2009 May 1;324(5927):651-4. doi: 10.1126/science.1171641. Epub 2009 Mar 19. Science. 2009. PMID: 19299583 Free PMC article.
Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes.
Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, Ivanova G, Omura C, Mo S, Vitaterna MH, Lopez JP, Philipson LH, Bradfield CA, Crosby SD, JeBailey L, Wang X, Takahashi JS, Bass J. Marcheva B, et al. Among authors: kobayashi y. Nature. 2010 Jul 29;466(7306):627-31. doi: 10.1038/nature09253. Nature. 2010. PMID: 20562852 Free PMC article.
Generation of N-ethyl-N-nitrosourea (ENU) diabetes models in mice demonstrates genotype-specific action of glucokinase activators.
Fenner D, Odili S, Hong HK, Kobayashi Y, Kohsaka A, Siepka SM, Vitaterna MH, Chen P, Zelent B, Grimsby J, Takahashi JS, Matschinsky FM, Bass J. Fenner D, et al. Among authors: kobayashi y. J Biol Chem. 2011 Nov 11;286(45):39560-72. doi: 10.1074/jbc.M111.269100. Epub 2011 Sep 15. J Biol Chem. 2011. PMID: 21921030 Free PMC article.
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice.
Peek CB, Affinati AH, Ramsey KM, Kuo HY, Yu W, Sena LA, Ilkayeva O, Marcheva B, Kobayashi Y, Omura C, Levine DC, Bacsik DJ, Gius D, Newgard CB, Goetzman E, Chandel NS, Denu JM, Mrksich M, Bass J. Peek CB, et al. Among authors: kobayashi y. Science. 2013 Nov 1;342(6158):1243417. doi: 10.1126/science.1243417. Epub 2013 Sep 19. Science. 2013. PMID: 24051248 Free PMC article.
A role for alternative splicing in circadian control of exocytosis and glucose homeostasis.
Marcheva B, Perelis M, Weidemann BJ, Taguchi A, Lin H, Omura C, Kobayashi Y, Newman MV, Wyatt EJ, McNally EM, Fox JEM, Hong H, Shankar A, Wheeler EC, Ramsey KM, MacDonald PE, Yeo GW, Bass J. Marcheva B, et al. Among authors: kobayashi y. Genes Dev. 2020 Aug 1;34(15-16):1089-1105. doi: 10.1101/gad.338178.120. Epub 2020 Jul 2. Genes Dev. 2020. PMID: 32616519 Free PMC article.
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