Tessier PM - Search Results

1

Selecting and engineering monoclonal antibodies with drug-like specificity.

Starr CG, Tessier PM. Starr CG, et al. Among authors: tessier pm. Curr Opin Biotechnol. 2019 Dec;60:119-127. doi: 10.1016/j.copbio.2019.01.008. Epub 2019 Feb 26. Curr Opin Biotechnol. 2019. PMID: 30822699 Free PMC article. Review.

2

Solution pH that minimizes self-association of three monoclonal antibodies is strongly dependent on ionic strength.

Sule SV, Cheung JK, Antochshuk V, Bhalla AS, Narasimhan C, Blaisdell S, Shameem M, Tessier PM. Sule SV, et al. Among authors: tessier pm. Mol Pharm. 2012 Apr 2;9(4):744-51. doi: 10.1021/mp200448j. Epub 2012 Feb 17. Mol Pharm. 2012. PMID: 22221144

3

Engineering aggregation-resistant antibodies.

Perchiacca JM, Tessier PM. Perchiacca JM, et al. Among authors: tessier pm. Annu Rev Chem Biomol Eng. 2012;3:263-86. doi: 10.1146/annurev-chembioeng-062011-081052. Epub 2012 Mar 29. Annu Rev Chem Biomol Eng. 2012. PMID: 22468604 Review.

4

Toward aggregation-resistant antibodies by design.

Lee CC, Perchiacca JM, Tessier PM. Lee CC, et al. Among authors: tessier pm. Trends Biotechnol. 2013 Nov;31(11):612-20. doi: 10.1016/j.tibtech.2013.07.002. Epub 2013 Aug 7. Trends Biotechnol. 2013. PMID: 23932102 Review.

5

Emerging methods for identifying monoclonal antibodies with low propensity to self-associate during the early discovery process.

Tessier PM, Wu J, Dickinson CD. Tessier PM, et al. Expert Opin Drug Deliv. 2014 Apr;11(4):461-5. doi: 10.1517/17425247.2014.876989. Epub 2014 Jan 21. Expert Opin Drug Deliv. 2014. PMID: 24444112

6

Improving monoclonal antibody selection and engineering using measurements of colloidal protein interactions.

Geng SB, Cheung JK, Narasimhan C, Shameem M, Tessier PM. Geng SB, et al. Among authors: tessier pm. J Pharm Sci. 2014 Nov;103(11):3356-3363. doi: 10.1002/jps.24130. Epub 2014 Sep 10. J Pharm Sci. 2014. PMID: 25209466 Free PMC article. Review.

7

Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs.

Tiller KE, Li L, Kumar S, Julian MC, Garde S, Tessier PM. Tiller KE, et al. Among authors: tessier pm. J Biol Chem. 2017 Oct 6;292(40):16638-16652. doi: 10.1074/jbc.M117.783837. Epub 2017 Aug 4. J Biol Chem. 2017. PMID: 28778924 Free PMC article.

8

Biophysical and Sequence-Based Methods for Identifying Monovalent and Bivalent Antibodies with High Colloidal Stability.

Alam ME, Geng SB, Bender C, Ludwig SD, Linden L, Hoet R, Tessier PM. Alam ME, et al. Among authors: tessier pm. Mol Pharm. 2018 Jan 2;15(1):150-163. doi: 10.1021/acs.molpharmaceut.7b00779. Epub 2017 Dec 6. Mol Pharm. 2018. PMID: 29154550

9

Net charge of antibody complementarity-determining regions is a key predictor of specificity.

Rabia LA, Zhang Y, Ludwig SD, Julian MC, Tessier PM. Rabia LA, et al. Among authors: tessier pm. Protein Eng Des Sel. 2018 Nov 1;31(11):409-418. doi: 10.1093/protein/gzz002. Protein Eng Des Sel. 2018. PMID: 30770934 Free PMC article.

10

Deamidation Can Compromise Antibody Colloidal Stability and Enhance Aggregation in a pH-Dependent Manner.

Alam ME, Barnett GV, Slaney TR, Starr CG, Das TK, Tessier PM. Alam ME, et al. Among authors: tessier pm. Mol Pharm. 2019 May 6;16(5):1939-1949. doi: 10.1021/acs.molpharmaceut.8b01311. Epub 2019 Apr 16. Mol Pharm. 2019. PMID: 30916563

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