Rojas A - Search Results

1

A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition.

Rojas A, Ganesh T, Wang W, Wang J, Dingledine R. Rojas A, et al. Neurobiol Dis. 2020 Jan;133:104399. doi: 10.1016/j.nbd.2019.02.010. Epub 2019 Feb 25. Neurobiol Dis. 2020. PMID: 30818067 Free PMC article. Review.

2

The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus.

Rojas A, Gueorguieva P, Lelutiu N, Quan Y, Shaw R, Dingledine R. Rojas A, et al. Neurobiol Dis. 2014 Oct;70:74-89. doi: 10.1016/j.nbd.2014.06.004. Epub 2014 Jun 19. Neurobiol Dis. 2014. PMID: 24952362 Free PMC article.

3

Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus.

Rojas A, Ganesh T, Lelutiu N, Gueorguieva P, Dingledine R. Rojas A, et al. Neuropharmacology. 2015 Jun;93:15-27. doi: 10.1016/j.neuropharm.2015.01.017. Epub 2015 Feb 3. Neuropharmacology. 2015. PMID: 25656476 Free PMC article.

4

Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus-induced deficits in the novel object recognition task in rats.

Rojas A, Ganesh T, Manji Z, O'neill T, Dingledine R. Rojas A, et al. Neuropharmacology. 2016 Nov;110(Pt A):419-430. doi: 10.1016/j.neuropharm.2016.07.028. Epub 2016 Jul 29. Neuropharmacology. 2016. PMID: 27477533 Free PMC article.

5

Novel Microglia Cell Line Expressing the Human EP2 Receptor.

Rojas A, Banik A, Chen D, Flood K, Ganesh T, Dingledine R. Rojas A, et al. ACS Chem Neurosci. 2019 Oct 16;10(10):4280-4292. doi: 10.1021/acschemneuro.9b00311. Epub 2019 Sep 11. ACS Chem Neurosci. 2019. PMID: 31469538

6

Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models.

Amaradhi R, Banik A, Mohammed S, Patro V, Rojas A, Wang W, Motati DR, Dingledine R, Ganesh T. Amaradhi R, et al. Among authors: rojas a. J Med Chem. 2020 Feb 13;63(3):1032-1050. doi: 10.1021/acs.jmedchem.9b01218. Epub 2020 Jan 16. J Med Chem. 2020. PMID: 31904232 Free PMC article.

7

Beneficial Outcome of Urethane Treatment Following Status Epilepticus in a Rat Organophosphorus Toxicity Model.

Rojas A, Wang W, Glover A, Manji Z, Fu Y, Dingledine R. Rojas A, et al. eNeuro. 2018 Apr 17;5(2):ENEURO.0070-18.2018. doi: 10.1523/ENEURO.0070-18.2018. eCollection 2018 Mar-Apr. eNeuro. 2018. PMID: 29766039 Free PMC article.

8

Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats.

Rojas A, Wang J, Glover A, Dingledine R. Rojas A, et al. Neurobiol Dis. 2020 Jul;140:104863. doi: 10.1016/j.nbd.2020.104863. Epub 2020 Apr 10. Neurobiol Dis. 2020. PMID: 32283202 Free PMC article.

9

Comparison of neuropathology in rats following status epilepticus induced by diisopropylfluorophosphate and soman.

Rojas A, McCarren HS, Wang J, Wang W, Abreu-Melon J, Wang S, McDonough JH, Dingledine R. Rojas A, et al. Neurotoxicology. 2021 Mar;83:14-27. doi: 10.1016/j.neuro.2020.12.010. Epub 2020 Dec 19. Neurotoxicology. 2021. PMID: 33352274 Free PMC article.

10

A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats.

Rojas A, Amaradhi R, Banik A, Jiang C, Abreu-Melon J, Wang S, Dingledine R, Ganesh T. Rojas A, et al. Neurotherapeutics. 2021 Apr;18(2):1207-1225. doi: 10.1007/s13311-020-00969-5. Epub 2021 Jan 6. Neurotherapeutics. 2021. PMID: 33410110 Free PMC article.

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