Price LS - Search Results

1

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis.

Booij TH, Price LS, Danen EHJ. Booij TH, et al. Among authors: price ls. SLAS Discov. 2019 Jul;24(6):615-627. doi: 10.1177/2472555219830087. Epub 2019 Feb 28. SLAS Discov. 2019. PMID: 30817892 Free PMC article.

2

Development of a 3D Tissue Culture-Based High-Content Screening Platform That Uses Phenotypic Profiling to Discriminate Selective Inhibitors of Receptor Tyrosine Kinases.

Booij TH, Klop MJ, Yan K, Szántai-Kis C, Szokol B, Orfi L, van de Water B, Keri G, Price LS. Booij TH, et al. Among authors: price ls. J Biomol Screen. 2016 Oct;21(9):912-22. doi: 10.1177/1087057116657269. Epub 2016 Jul 7. J Biomol Screen. 2016. PMID: 27412535 Free PMC article.

3

High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease.

Booij TH, Bange H, Leonhard WN, Yan K, Fokkelman M, Kunnen SJ, Dauwerse JG, Qin Y, van de Water B, van Westen GJP, Peters DJM, Price LS. Booij TH, et al. Among authors: price ls. SLAS Discov. 2017 Sep;22(8):974-984. doi: 10.1177/2472555217716056. Epub 2017 Jun 23. SLAS Discov. 2017. PMID: 28644734 Free PMC article.

4

Automated microinjection of cell-polymer suspensions in 3D ECM scaffolds for high-throughput quantitative cancer invasion screens.

Truong HH, de Sonneville J, Ghotra VP, Xiong J, Price L, Hogendoorn PC, Spaink HH, van de Water B, Danen EH. Truong HH, et al. Biomaterials. 2012 Jan;33(1):181-8. doi: 10.1016/j.biomaterials.2011.09.049. Epub 2011 Oct 20. Biomaterials. 2012. PMID: 22018386

5

Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.

Baranski Z, Booij TH, Cleton-Jansen AM, Price LS, van de Water B, Bovée JV, Hogendoorn PC, Danen EH. Baranski Z, et al. Among authors: price ls. J Pathol. 2015 Jul;236(3):348-59. doi: 10.1002/path.4528. Epub 2015 Mar 30. J Pathol. 2015. PMID: 25757065

6

In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease.

Booij TH, Leonhard WN, Bange H, Yan K, Fokkelman M, Plugge AJ, Veraar KAM, Dauwerse JG, van Westen GJP, van de Water B, Price LS, Peters DJM. Booij TH, et al. Among authors: price ls. J Mol Cell Biol. 2020 Aug 1;12(8):644-653. doi: 10.1093/jmcb/mjz029. J Mol Cell Biol. 2020. PMID: 31065693 Free PMC article.

7

Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells.

Verissimo CS, Cheng S, Puigvert JC, Qin Y, Vroon A, van Deutekom J, Price LS, Danen EH, van de Water B, Fitzsimons CP, Vreugdenhil E. Verissimo CS, et al. Among authors: price ls. J Pharmacol Exp Ther. 2012 Jul;342(1):119-30. doi: 10.1124/jpet.111.188813. Epub 2012 Apr 6. J Pharmacol Exp Ther. 2012. PMID: 22490379

8

Epac-Rap signaling reduces oxidative stress in the tubular epithelium.

Stokman G, Qin Y, Booij TH, Ramaiahgari S, Lacombe M, Dolman ME, van Dorenmalen KM, Teske GJ, Florquin S, Schwede F, van de Water B, Kok RJ, Price LS. Stokman G, et al. Among authors: price ls. J Am Soc Nephrol. 2014 Jul;25(7):1474-85. doi: 10.1681/ASN.2013070679. Epub 2014 Feb 7. J Am Soc Nephrol. 2014. PMID: 24511123 Free PMC article.

9

MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation.

Baranski Z, Booij TH, Kuijjer ML, de Jong Y, Cleton-Jansen AM, Price LS, van de Water B, Bovée JV, Hogendoorn PC, Danen EH. Baranski Z, et al. Among authors: price ls. Genes Cancer. 2015 Nov;6(11-12):503-12. doi: 10.18632/genesandcancer.91. Genes Cancer. 2015. PMID: 26807203 Free PMC article.

10

Screening out irrelevant cell-based models of disease.

Horvath P, Aulner N, Bickle M, Davies AM, Nery ED, Ebner D, Montoya MC, Östling P, Pietiäinen V, Price LS, Shorte SL, Turcatti G, von Schantz C, Carragher NO. Horvath P, et al. Among authors: price ls. Nat Rev Drug Discov. 2016 Nov;15(11):751-769. doi: 10.1038/nrd.2016.175. Epub 2016 Sep 12. Nat Rev Drug Discov. 2016. PMID: 27616293 Review.

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