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NR4A transcription factors limit CAR T cell function in solid tumours.
Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A. Chen J, et al. Among authors: rao a. Nature. 2019 Mar;567(7749):530-534. doi: 10.1038/s41586-019-0985-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814732 Free PMC article.
Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility.
Seumois G, Chavez L, Gerasimova A, Lienhard M, Omran N, Kalinke L, Vedanayagam M, Ganesan AP, Chawla A, Djukanović R, Ansel KM, Peters B, Rao A, Vijayanand P. Seumois G, et al. Among authors: rao a. Nat Immunol. 2014 Aug;15(8):777-88. doi: 10.1038/ni.2937. Epub 2014 Jul 6. Nat Immunol. 2014. PMID: 24997565 Free PMC article.
Jarid2 is induced by TCR signalling and controls iNKT cell maturation.
Pereira RM, Martinez GJ, Engel I, Cruz-Guilloty F, Barboza BA, Tsagaratou A, Lio CW, Berg LJ, Lee Y, Kronenberg M, Bandukwala HS, Rao A. Pereira RM, et al. Among authors: rao a. Nat Commun. 2014 Aug 8;5:4540. doi: 10.1038/ncomms5540. Nat Commun. 2014. PMID: 25105474 Free PMC article.
The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.
Martinez GJ, Pereira RM, Äijö T, Kim EY, Marangoni F, Pipkin ME, Togher S, Heissmeyer V, Zhang YC, Crotty S, Lamperti ED, Ansel KM, Mempel TR, Lähdesmäki H, Hogan PG, Rao A. Martinez GJ, et al. Among authors: rao a. Immunity. 2015 Feb 17;42(2):265-278. doi: 10.1016/j.immuni.2015.01.006. Epub 2015 Feb 10. Immunity. 2015. PMID: 25680272 Free PMC article.
6,172 results