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Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.
Elia I, Rossi M, Stegen S, Broekaert D, Doglioni G, van Gorsel M, Boon R, Escalona-Noguero C, Torrekens S, Verfaillie C, Verbeken E, Carmeliet G, Fendt SM. Elia I, et al. Among authors: stegen s. Nature. 2019 Apr;568(7750):117-121. doi: 10.1038/s41586-019-0977-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814728 Free PMC article.
Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways.
Manesia JK, Xu Z, Broekaert D, Boon R, van Vliet A, Eelen G, Vanwelden T, Stegen S, Van Gastel N, Pascual-Montano A, Fendt SM, Carmeliet G, Carmeliet P, Khurana S, Verfaillie CM. Manesia JK, et al. Among authors: stegen s. Stem Cell Res. 2015 Nov;15(3):715-721. doi: 10.1016/j.scr.2015.11.001. Epub 2015 Nov 9. Stem Cell Res. 2015. PMID: 26599326 Free article.
HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival.
Stegen S, van Gastel N, Eelen G, Ghesquière B, D'Anna F, Thienpont B, Goveia J, Torrekens S, Van Looveren R, Luyten FP, Maxwell PH, Wielockx B, Lambrechts D, Fendt SM, Carmeliet P, Carmeliet G. Stegen S, et al. Cell Metab. 2016 Feb 9;23(2):265-79. doi: 10.1016/j.cmet.2016.01.002. Cell Metab. 2016. PMID: 26863487 Free PMC article.
The vasculature: a vessel for bone metastasis.
Raymaekers K, Stegen S, van Gastel N, Carmeliet G. Raymaekers K, et al. Among authors: stegen s. Bonekey Rep. 2015 Sep 9;4:742. doi: 10.1038/bonekey.2015.111. eCollection 2015. Bonekey Rep. 2015. PMID: 27217954 Free PMC article. Review.
79 results