Ooi J - Search Results

1

Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects.

Ooi J, Langley SR, Xu X, Utami KH, Sim B, Huang Y, Harmston NP, Tay YL, Ziaei A, Zeng R, Low D, Aminkeng F, Sobota RM, Ginhoux F, Petretto E, Pouladi MA. Ooi J, et al. Cell Rep. 2019 Feb 26;26(9):2494-2508.e7. doi: 10.1016/j.celrep.2019.02.008. Cell Rep. 2019. PMID: 30811996 Free article.

2

Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells.

Xu X, Tay Y, Sim B, Yoon SI, Huang Y, Ooi J, Utami KH, Ziaei A, Ng B, Radulescu C, Low D, Ng AYJ, Loh M, Venkatesh B, Ginhoux F, Augustine GJ, Pouladi MA. Xu X, et al. Among authors: ooi j. Stem Cell Reports. 2017 Mar 14;8(3):619-633. doi: 10.1016/j.stemcr.2017.01.022. Epub 2017 Feb 23. Stem Cell Reports. 2017. PMID: 28238795 Free PMC article.

3

Inhibition of Excessive Monoamine Oxidase A/B Activity Protects Against Stress-induced Neuronal Death in Huntington Disease.

Ooi J, Hayden MR, Pouladi MA. Ooi J, et al. Mol Neurobiol. 2015 Dec;52(3):1850-1861. doi: 10.1007/s12035-014-8974-4. Epub 2014 Nov 15. Mol Neurobiol. 2015. PMID: 25398695 Free PMC article.

4

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes.

Maillet A, Tan K, Chai X, Sadananda SN, Mehta A, Ooi J, Hayden MR, Pouladi MA, Ghosh S, Shim W, Brunham LR. Maillet A, et al. Among authors: ooi j. Sci Rep. 2016 May 4;6:25333. doi: 10.1038/srep25333. Sci Rep. 2016. PMID: 27142468 Free PMC article.

5

Gene expression profiles complement the analysis of genomic modifiers of the clinical onset of Huntington disease.

Wright GEB, Caron NS, Ng B, Casal L, Casazza W, Xu X, Ooi J, Pouladi MA, Mostafavi S, Ross CJD, Hayden MR. Wright GEB, et al. Among authors: ooi j. Hum Mol Genet. 2020 Sep 29;29(16):2788-2802. doi: 10.1093/hmg/ddaa184. Hum Mol Genet. 2020. PMID: 32898862 Free PMC article.

6

Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease.

Garcia-Miralles M, Ooi J, Ferrari Bardile C, Tan LJ, George M, Drum CL, Lin RY, Hayden MR, Pouladi MA. Garcia-Miralles M, et al. Among authors: ooi j. Exp Neurol. 2016 Apr;278:4-10. doi: 10.1016/j.expneurol.2016.01.019. Epub 2016 Jan 26. Exp Neurol. 2016. PMID: 26825854 Free article.

7

A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.

Southwell AL, Skotte NH, Villanueva EB, Østergaard ME, Gu X, Kordasiewicz HB, Kay C, Cheung D, Xie Y, Waltl S, Dal Cengio L, Findlay-Black H, Doty CN, Petoukhov E, Iworima D, Slama R, Ooi J, Pouladi MA, Yang XW, Swayze EE, Seth PP, Hayden MR. Southwell AL, et al. Among authors: ooi j. Hum Mol Genet. 2017 Mar 15;26(6):1115-1132. doi: 10.1093/hmg/ddx021. Hum Mol Genet. 2017. PMID: 28104789

8

Mutations in C2CD3 cause oral-facial-digital syndrome through deregulation of centriole length.

Ooi J. Ooi J. Clin Genet. 2015 Apr;87(4):328-9. doi: 10.1111/cge.12545. Epub 2014 Dec 18. Clin Genet. 2015. PMID: 25421854 No abstract available.

9

Reprogramming to pluripotency using designer TALE transcription factors targeting enhancers.

Gao X, Yang J, Tsang JC, Ooi J, Wu D, Liu P. Gao X, et al. Among authors: ooi j. Stem Cell Reports. 2013 Jul 11;1(2):183-97. doi: 10.1016/j.stemcr.2013.06.002. eCollection 2013. Stem Cell Reports. 2013. PMID: 24052952 Free PMC article.

10

Delineating nuclear reprogramming.

Ooi J, Liu P. Ooi J, et al. Protein Cell. 2012 May;3(5):329-45. doi: 10.1007/s13238-012-2920-x. Epub 2012 Mar 31. Protein Cell. 2012. PMID: 22467264 Free PMC article. Review.

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