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Neutrophil exosomes enhance the skin autoinflammation in generalized pustular psoriasis via activating keratinocytes.
Shao S, Fang H, Zhang J, Jiang M, Xue K, Ma J, Zhang J, Lei J, Zhang Y, Li B, Yuan X, Dang E, Wang G. Shao S, et al. Among authors: yuan x. FASEB J. 2019 Jun;33(6):6813-6828. doi: 10.1096/fj.201802090RR. Epub 2019 Feb 27. FASEB J. 2019. PMID: 30811955
Neutrophils isolated from patients with GPP induced higher expressions of inflammatory genes including IL-1beta, IL-36G, IL-18, TNF-alpha, and C-X-C motif chemokine ligands in keratinocytes than normal neutrophils did. Moreover, neutrophils from patients with GPP secreted …
Neutrophils isolated from patients with GPP induced higher expressions of inflammatory genes including IL-1beta, IL-36G, IL-18, TNF-alpha, a …
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