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Page 1
Uric Acid-Induced Enhancements of Kv1.5 Protein Expression and Channel Activity via the Akt-HSF1-Hsp70 Pathway in HL-1 Atrial Myocytes.
Taufiq F, Maharani N, Li P, Kurata Y, Ikeda N, Kuwabara M, Otani N, Miake J, Hasegawa A, Tsuneto M, Shirayoshi Y, Ninomiya H, Saitoh T, Nakai A, Yamamoto K, Hisatome I. Taufiq F, et al. Among authors: nakai a. Circ J. 2019 Mar 25;83(4):718-726. doi: 10.1253/circj.CJ-18-1088. Epub 2019 Feb 20. Circ J. 2019. PMID: 30787218 Free article.
HSF1 and constitutively active HSF1 improve vascular endothelial function (heat shock proteins improve vascular endothelial function).
Uchiyama T, Atsuta H, Utsugi T, Oguri M, Hasegawa A, Nakamura T, Nakai A, Nakata M, Maruyama I, Tomura H, Okajima F, Tomono S, Kawazu S, Nagai R, Kurabayashi M. Uchiyama T, et al. Among authors: nakai a. Atherosclerosis. 2007 Feb;190(2):321-9. doi: 10.1016/j.atherosclerosis.2006.03.037. Epub 2006 May 5. Atherosclerosis. 2007. PMID: 16678833
Functional stabilization of Kv1.5 protein by Hsp70 in mammalian cell lines.
Hirota Y, Kurata Y, Kato M, Notsu T, Koshida S, Inoue T, Kawata Y, Miake J, Bahrudin U, Li P, Hoshikawa Y, Yamamoto Y, Igawa O, Shirayoshi Y, Nakai A, Ninomiya H, Higaki K, Hiraoka M, Hisatome I. Hirota Y, et al. Among authors: nakai a. Biochem Biophys Res Commun. 2008 Aug 1;372(3):469-74. doi: 10.1016/j.bbrc.2008.05.068. Epub 2008 May 23. Biochem Biophys Res Commun. 2008. PMID: 18502196
Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells.
Ting YK, Morikawa K, Kurata Y, Li P, Bahrudin U, Mizuta E, Kato M, Miake J, Yamamoto Y, Yoshida A, Murata M, Inoue T, Nakai A, Shiota G, Higaki K, Nanba E, Ninomiya H, Shirayoshi Y, Hisatome I. Ting YK, et al. Among authors: nakai a. Br J Pharmacol. 2011 Apr;162(8):1832-42. doi: 10.1111/j.1476-5381.2011.01204.x. Br J Pharmacol. 2011. PMID: 21232033 Free PMC article.
Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.
Iwai C, Li P, Kurata Y, Hoshikawa Y, Morikawa K, Maharani N, Higaki K, Sasano T, Notsu T, Ishido Y, Miake J, Yamamoto Y, Shirayoshi Y, Ninomiya H, Nakai A, Murata S, Yoshida A, Yamamoto K, Hiraoka M, Hisatome I. Iwai C, et al. Among authors: nakai a. Cardiovasc Res. 2013 Dec 1;100(3):520-8. doi: 10.1093/cvr/cvt200. Epub 2013 Aug 20. Cardiovasc Res. 2013. PMID: 23963841
Characterization of the novel mutant A78T-HERG from a long QT syndrome type 2 patient: Instability of the mutant protein and stabilization by heat shock factor 1.
Kondo T, Hisatome I, Yoshimura S, Mahati E, Notsu T, Li P, Iitsuka K, Kato M, Ogura K, Miake J, Aiba T, Shimizu W, Kurata Y, Sakata S, Nakasone N, Ninomiya H, Nakai A, Higaki K, Kawata Y, Shirayoshi Y, Yoshida A, Yamamoto K. Kondo T, et al. Among authors: nakai a. J Arrhythm. 2016 Oct;32(5):433-440. doi: 10.1016/j.joa.2015.10.005. Epub 2015 Nov 25. J Arrhythm. 2016. PMID: 27761169 Free PMC article.
M3 Muscarinic Receptor Signaling Stabilizes a Novel Mutant Human Ether-a-Go-Go-Related Gene Channel Protein via Phosphorylation of Heat Shock Factor 1 in Transfected Cells.
Mahati E, Li P, Kurata Y, Maharani N, Ikeda N, Sakata S, Ogura K, Miake J, Aiba T, Shimizu W, Nakasone N, Ninomiya H, Higaki K, Yamamoto K, Nakai A, Shirayoshi Y, Hisatome I. Mahati E, et al. Among authors: nakai a. Circ J. 2016 Nov 25;80(12):2443-2452. doi: 10.1253/circj.CJ-16-0712. Epub 2016 Nov 1. Circ J. 2016. PMID: 27803431 Free article.
603 results