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Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model.

Kose HB, Larsen NB, Duxin JP, Yardimci H. Kose HB, et al. Cell Rep. 2019 Feb 19;26(8):2113-2125.e6. doi: 10.1016/j.celrep.2019.01.086. Cell Rep. 2019. PMID: 30784593 Free PMC article.

The mechanism of DNA unwinding by the eukaryotic replicative helicase.

Burnham DR, Kose HB, Hoyle RB, Yardimci H. Burnham DR, et al. Among authors: kose hb. Nat Commun. 2019 May 14;10(1):2159. doi: 10.1038/s41467-019-09896-2. Nat Commun. 2019. PMID: 31089141 Free PMC article.

Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome.

Eickhoff P, Kose HB, Martino F, Petojevic T, Abid Ali F, Locke J, Tamberg N, Nans A, Berger JM, Botchan MR, Yardimci H, Costa A. Eickhoff P, et al. Among authors: kose hb. Cell Rep. 2019 Sep 3;28(10):2673-2688.e8. doi: 10.1016/j.celrep.2019.07.104. Cell Rep. 2019. PMID: 31484077 Free PMC article.

Duplex DNA engagement and RPA oppositely regulate the DNA-unwinding rate of CMG helicase.

Kose HB, Xie S, Cameron G, Strycharska MS, Yardimci H. Kose HB, et al. Nat Commun. 2020 Jul 24;11(1):3713. doi: 10.1038/s41467-020-17443-7. Nat Commun. 2020. PMID: 32709841 Free PMC article.

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