Manning BD - Search Results

1

Author Correction: Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: manning bd. Nat Cell Biol. 2019 May;21(5):662-663. doi: 10.1038/s41556-019-0280-y. Nat Cell Biol. 2019. PMID: 30783264

2

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway.

Manning BD, Tee AR, Logsdon MN, Blenis J, Cantley LC. Manning BD, et al. Mol Cell. 2002 Jul;10(1):151-62. doi: 10.1016/s1097-2765(02)00568-3. Mol Cell. 2002. PMID: 12150915 Free article.

3

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling.

Tee AR, Fingar DC, Manning BD, Kwiatkowski DJ, Cantley LC, Blenis J. Tee AR, et al. Among authors: manning bd. Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13571-6. doi: 10.1073/pnas.202476899. Epub 2002 Sep 23. Proc Natl Acad Sci U S A. 2002. PMID: 12271141 Free PMC article.

4

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.

Tee AR, Manning BD, Roux PP, Cantley LC, Blenis J. Tee AR, et al. Among authors: manning bd. Curr Biol. 2003 Aug 5;13(15):1259-68. doi: 10.1016/s0960-9822(03)00506-2. Curr Biol. 2003. PMID: 12906785 Free article.

5

Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis.

Manning BD. Manning BD. J Cell Biol. 2004 Nov 8;167(3):399-403. doi: 10.1083/jcb.200408161. J Cell Biol. 2004. PMID: 15533996 Free PMC article. Review.

6

AKT/PKB signaling: navigating downstream.

Manning BD, Cantley LC. Manning BD, et al. Cell. 2007 Jun 29;129(7):1261-74. doi: 10.1016/j.cell.2007.06.009. Cell. 2007. PMID: 17604717 Free PMC article. Review.

7

Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1.

Dibble CC, Asara JM, Manning BD. Dibble CC, et al. Among authors: manning bd. Mol Cell Biol. 2009 Nov;29(21):5657-70. doi: 10.1128/MCB.00735-09. Epub 2009 Aug 31. Mol Cell Biol. 2009. PMID: 19720745 Free PMC article.

8

Common corruption of the mTOR signaling network in human tumors.

Menon S, Manning BD. Menon S, et al. Among authors: manning bd. Oncogene. 2008 Dec;27 Suppl 2(0 2):S43-51. doi: 10.1038/onc.2009.352. Oncogene. 2008. PMID: 19956179 Free PMC article. Review.

9

Activation of a metabolic gene regulatory network downstream of mTOR complex 1.

Düvel K, Yecies JL, Menon S, Raman P, Lipovsky AI, Souza AL, Triantafellow E, Ma Q, Gorski R, Cleaver S, Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, Manning BD. Düvel K, et al. Among authors: manning bd. Mol Cell. 2010 Jul 30;39(2):171-83. doi: 10.1016/j.molcel.2010.06.022. Mol Cell. 2010. PMID: 20670887 Free PMC article.

10

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways.

Yecies JL, Zhang HH, Menon S, Liu S, Yecies D, Lipovsky AI, Gorgun C, Kwiatkowski DJ, Hotamisligil GS, Lee CH, Manning BD. Yecies JL, et al. Among authors: manning bd. Cell Metab. 2011 Jul 6;14(1):21-32. doi: 10.1016/j.cmet.2011.06.002. Cell Metab. 2011. PMID: 21723501 Free PMC article.

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