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Page 1
Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands.
Sakyiamah MM, Kobayakawa T, Fujino M, Konno M, Narumi T, Tanaka T, Nomura W, Yamamoto N, Murakami T, Tamamura H. Sakyiamah MM, et al. Among authors: tamamura h. Bioorg Med Chem. 2019 Mar 15;27(6):1130-1138. doi: 10.1016/j.bmc.2019.02.013. Epub 2019 Feb 6. Bioorg Med Chem. 2019. PMID: 30772128
Structure-activity relationships of an anti-HIV peptide, T22.
Tamamura H, Murakami T, Masuda M, Otaka A, Takada W, Ibuka T, Nakashima H, Waki M, Matsumoto A, Yamamoto N, et al. Tamamura H, et al. Biochem Biophys Res Commun. 1994 Dec 30;205(3):1729-35. doi: 10.1006/bbrc.1994.2868. Biochem Biophys Res Commun. 1994. PMID: 7811258
Interaction of an anti-HIV peptide, T22, with gp120 and CD4.
Tamamura H, Otaka A, Murakami T, Ishihara T, Ibuka T, Waki M, Matsumoto A, Yamamoto N, Fujii N. Tamamura H, et al. Biochem Biophys Res Commun. 1996 Feb 15;219(2):555-9. doi: 10.1006/bbrc.1996.0272. Biochem Biophys Res Commun. 1996. PMID: 8605026
An anti-HIV peptide, T22, forms a highly active complex with Zn(II).
Tamamura H, Otaka A, Murakami T, Ibuka T, Sakano K, Waki M, Matsumoto A, Yamamoto N, Fujii N. Tamamura H, et al. Biochem Biophys Res Commun. 1996 Dec 13;229(2):648-52. doi: 10.1006/bbrc.1996.1858. Biochem Biophys Res Commun. 1996. PMID: 8954952
A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection.
Murakami T, Nakajima T, Koyanagi Y, Tachibana K, Fujii N, Tamamura H, Yoshida N, Waki M, Matsumoto A, Yoshie O, Kishimoto T, Yamamoto N, Nagasawa T. Murakami T, et al. Among authors: tamamura h. J Exp Med. 1997 Oct 20;186(8):1389-93. doi: 10.1084/jem.186.8.1389. J Exp Med. 1997. PMID: 9334379 Free PMC article.
Pharmacophore identification of a chemokine receptor (CXCR4) antagonist, T22 ([Tyr(5,12),Lys7]-polyphemusin II), which specifically blocks T cell-line-tropic HIV-1 infection.
Tamamura H, Imai M, Ishihara T, Masuda M, Funakoshi H, Oyake H, Murakami T, Arakaki R, Nakashima H, Otaka A, Ibuka T, Waki M, Matsumoto A, Yamamoto N, Fujii N. Tamamura H, et al. Bioorg Med Chem. 1998 Jul;6(7):1033-41. doi: 10.1016/s0968-0896(98)00061-3. Bioorg Med Chem. 1998. PMID: 9730240
287 results