Roninson I - Search Results

1

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein.

Alam A, Kowal J, Broude E, Roninson I, Locher KP. Alam A, et al. Among authors: roninson i. Science. 2019 Feb 15;363(6428):753-756. doi: 10.1126/science.aav7102. Science. 2019. PMID: 30765569 Free PMC article.

2

A senescence-like phenotype distinguishes tumor cells that undergo terminal proliferation arrest after exposure to anticancer agents.

Chang BD, Broude EV, Dokmanovic M, Zhu H, Ruth A, Xuan Y, Kandel ES, Lausch E, Christov K, Roninson IB. Chang BD, et al. Among authors: roninson ib. Cancer Res. 1999 Aug 1;59(15):3761-7. Cancer Res. 1999. PMID: 10446993

3

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs.

Chang BD, Xuan Y, Broude EV, Zhu H, Schott B, Fang J, Roninson IB. Chang BD, et al. Among authors: roninson ib. Oncogene. 1999 Aug 26;18(34):4808-18. doi: 10.1038/sj.onc.1203078. Oncogene. 1999. PMID: 10490814

4

p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells.

Chang BD, Broude EV, Fang J, Kalinichenko TV, Abdryashitov R, Poole JC, Roninson IB. Chang BD, et al. Among authors: roninson ib. Oncogene. 2000 Apr 20;19(17):2165-70. doi: 10.1038/sj.onc.1203573. Oncogene. 2000. PMID: 10815808

5

Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent.

Chang BD, Swift ME, Shen M, Fang J, Broude EV, Roninson IB. Chang BD, et al. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):389-94. doi: 10.1073/pnas.012602599. Epub 2001 Dec 18. Proc Natl Acad Sci U S A. 2002. PMID: 11752408 Free PMC article.

6

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells.

Roninson IB, Broude EV, Chang BD. Roninson IB, et al. Drug Resist Updat. 2001 Oct;4(5):303-13. doi: 10.1054/drup.2001.0213. Drug Resist Updat. 2001. PMID: 11991684 Review.

7

Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1.

Shtutman M, Baig M, Levina E, Hurteau G, Lim CU, Broude E, Nikiforov M, Harkins TT, Carmack CS, Ding Y, Wieland F, Buttyan R, Roninson IB. Shtutman M, et al. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12449-54. doi: 10.1073/pnas.1103842108. Epub 2011 Jul 11. Proc Natl Acad Sci U S A. 2011. PMID: 21746916 Free PMC article.

8

Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.

Porter DC, Farmaki E, Altilia S, Schools GP, West DK, Chen M, Chang BD, Puzyrev AT, Lim CU, Rokow-Kittell R, Friedhoff LT, Papavassiliou AG, Kalurupalle S, Hurteau G, Shi J, Baran PS, Gyorffy B, Wentland MP, Broude EV, Kiaris H, Roninson IB. Porter DC, et al. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13799-804. doi: 10.1073/pnas.1206906109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869755 Free PMC article.

9

Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.

Levina E, Ji H, Chen M, Baig M, Oliver D, Ohouo P, Lim CU, Schools G, Carmack S, Ding Y, Broude EV, Roninson IB, Buttyan R, Shtutman M. Levina E, et al. Oncotarget. 2015 May 30;6(15):13088-104. doi: 10.18632/oncotarget.3743. Oncotarget. 2015. PMID: 26036626 Free PMC article.

10

Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer.

Broude EV, Győrffy B, Chumanevich AA, Chen M, McDermott MS, Shtutman M, Catroppo JF, Roninson IB. Broude EV, et al. Curr Cancer Drug Targets. 2015;15(8):739-49. doi: 10.2174/156800961508151001105814. Curr Cancer Drug Targets. 2015. PMID: 26452386 Free PMC article. Review.

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