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Page 1
Selective TASK-1 Inhibitor with a Defined Structure-Activity Relationship Reduces Cancer Cell Proliferation and Viability.
Arévalo B, Bedoya M, Kiper AK, Vergara F, Ramírez D, Mazola Y, Bustos D, Zúñiga R, Cikutovic R, Cayo A, Rinné S, Ramirez-Apan MT, Sepúlveda FV, Cerda O, López-Collazo E, Decher N, Zúñiga L, Gutierrez M, González W. Arévalo B, et al. Among authors: decher n. J Med Chem. 2022 Nov 24;65(22):15014-15027. doi: 10.1021/acs.jmedchem.1c00378. Epub 2022 Nov 15. J Med Chem. 2022. PMID: 36378530
Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function.
Vera-Zambrano A, Baena-Nuevo M, Rinné S, Villegas-Esguevillas M, Barreira B, Telli G, de Benito-Bueno A, Blázquez JA, Climent B, Pérez-Vizcaino F, Valenzuela C, Decher N, Gonzalez T, Cogolludo A. Vera-Zambrano A, et al. Among authors: decher n. Pharmacol Res. 2023 Mar;189:106684. doi: 10.1016/j.phrs.2023.106684. Epub 2023 Feb 3. Pharmacol Res. 2023. PMID: 36740150 Free article.
SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake.
Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM. Honrath B, et al. Among authors: decher n. Cell Death Differ. 2017 May;24(5):761-773. doi: 10.1038/cdd.2017.2. Epub 2017 Mar 10. Cell Death Differ. 2017. PMID: 28282037 Free PMC article.
The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.
Silbernagel N, Walecki M, Schäfer MK, Kessler M, Zobeiri M, Rinné S, Kiper AK, Komadowski MA, Vowinkel KS, Wemhöner K, Fortmüller L, Schewe M, Dolga AM, Scekic-Zahirovic J, Matschke LA, Culmsee C, Baukrowitz T, Monassier L, Ullrich ND, Dupuis L, Just S, Budde T, Fabritz L, Decher N. Silbernagel N, et al. Among authors: decher n. FASEB J. 2018 Nov;32(11):6159-6173. doi: 10.1096/fj.201800246R. Epub 2018 Jun 7. FASEB J. 2018. PMID: 29879376 Free PMC article.
The critical function of VAPB in native pacemaker channel complexes will be relevant for our understanding of cardiac arrhythmias and epilepsies, and provides an unexpected link between these diseases and amyotrophic lateral sclerosis.-Silbernagel, N., Walecki, M., Schafer …
The critical function of VAPB in native pacemaker channel complexes will be relevant for our understanding of cardiac arrhythmias and epilep …
109 results