O'Donoghue AJ - Search Results

1

Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome.

Quinn RA, Adem S, Mills RH, Comstock W, DeRight Goldasich L, Humphrey G, Aksenov AA, Melnik AV, da Silva R, Ackermann G, Bandeira N, Gonzalez DJ, Conrad D, O'Donoghue AJ, Knight R, Dorrestein PC. Quinn RA, et al. Microbiome. 2019 Feb 13;7(1):23. doi: 10.1186/s40168-019-0636-3. Microbiome. 2019. PMID: 30760325 Free PMC article.

2

Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry.

Lapek JD Jr, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ. Lapek JD Jr, et al. Mol Cell Proteomics. 2019 May;18(5):968-981. doi: 10.1074/mcp.TIR118.001099. Epub 2019 Jan 31. Mol Cell Proteomics. 2019. PMID: 30705125 Free PMC article.

3

Giant magnetoresistive biosensors for real-time quantitative detection of protease activity.

Adem S, Jain S, Sveiven M, Zhou X, O'Donoghue AJ, Hall DA. Adem S, et al. Sci Rep. 2020 May 14;10(1):7941. doi: 10.1038/s41598-020-62910-2. Sci Rep. 2020. PMID: 32409675 Free PMC article.

4

Native metabolomics identifies the rivulariapeptolide family of protease inhibitors.

Reher R, Aron AT, Fajtová P, Stincone P, Wagner B, Pérez-Lorente AI, Liu C, Shalom IYB, Bittremieux W, Wang M, Jeong K, Matos-Hernandez ML, Alexander KL, Caro-Diaz EJ, Naman CB, Scanlan JHW, Hochban PMM, Diederich WE, Molina-Santiago C, Romero D, Selim KA, Sass P, Brötz-Oesterhelt H, Hughes CC, Dorrestein PC, O'Donoghue AJ, Gerwick WH, Petras D. Reher R, et al. Nat Commun. 2022 Aug 8;13(1):4619. doi: 10.1038/s41467-022-32016-6. Nat Commun. 2022. PMID: 35941113 Free PMC article.

5

The Pseudomonas aeruginosa protease LasB directly activates IL-1β.

Sun J, LaRock DL, Skowronski EA, Kimmey JM, Olson J, Jiang Z, O'Donoghue AJ, Nizet V, LaRock CN. Sun J, et al. EBioMedicine. 2020 Oct;60:102984. doi: 10.1016/j.ebiom.2020.102984. Epub 2020 Sep 23. EBioMedicine. 2020. PMID: 32979835 Free PMC article.

6

Characterization of a multimeric, eukaryotic prolyl aminopeptidase: an inducible and highly specific intracellular peptidase from the non-pathogenic fungus Talaromyces emersonii.

Mahon CS, O'Donoghue AJ, Goetz DH, Murray PG, Craik CS, Tuohy MG. Mahon CS, et al. Microbiology (Reading). 2009 Nov;155(Pt 11):3673-3682. doi: 10.1099/mic.0.030940-0. Epub 2009 Jun 25. Microbiology (Reading). 2009. PMID: 19556294 Free PMC article.

7

Global identification of peptidase specificity by multiplex substrate profiling.

O'Donoghue AJ, Eroy-Reveles AA, Knudsen GM, Ingram J, Zhou M, Statnekov JB, Greninger AL, Hostetter DR, Qu G, Maltby DA, Anderson MO, Derisi JL, McKerrow JH, Burlingame AL, Craik CS. O'Donoghue AJ, et al. Nat Methods. 2012 Nov;9(11):1095-100. doi: 10.1038/nmeth.2182. Epub 2012 Sep 30. Nat Methods. 2012. PMID: 23023596 Free PMC article.

8

Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase.

O'Donoghue AJ, Jin Y, Knudsen GM, Perera NC, Jenne DE, Murphy JE, Craik CS, Hermiston TW. O'Donoghue AJ, et al. PLoS One. 2013 Sep 20;8(9):e75141. doi: 10.1371/journal.pone.0075141. eCollection 2013. PLoS One. 2013. PMID: 24073241 Free PMC article.

9

Quantitative MS-based enzymology of caspases reveals distinct protein substrate specificities, hierarchies, and cellular roles.

Julien O, Zhuang M, Wiita AP, O'Donoghue AJ, Knudsen GM, Craik CS, Wells JA. Julien O, et al. Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):E2001-10. doi: 10.1073/pnas.1524900113. Epub 2016 Mar 22. Proc Natl Acad Sci U S A. 2016. PMID: 27006500 Free PMC article.

10

Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria.

Goupil LS, Ivry SL, Hsieh I, Suzuki BM, Craik CS, O'Donoghue AJ, McKerrow JH. Goupil LS, et al. PLoS Negl Trop Dis. 2016 Aug 8;10(8):e0004893. doi: 10.1371/journal.pntd.0004893. eCollection 2016 Aug. PLoS Negl Trop Dis. 2016. PMID: 27501047 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

129 results

Search Page

Filters